DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hkb and Klf15

DIOPT Version :9

Sequence 1:	NP_524221.1	Gene:	hkb / 40549	FlyBaseID:	FBgn0261434	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_572185.1	Gene:	Klf15 / 31410	FlyBaseID:	FBgn0025679	Length:	311	Species:	Drosophila melanogaster

Alignment Length:	282	Identity:	74/282 - (26%)
Similarity:	114/282 - (40%)	Gaps:	89/282 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 GDFSSASSSAS-SSSNSSKSCYEEA-------LNHSSYTRTSTPLLDAAPH-------------- 100
            |:|.|.....| |..|.::..:||:       |:.::.|.|:..:....||
  Fly    34 GEFDSTYVDTSFSGGNYNQLEFEESDYYGIITLDSNNNTNTNGNIQVGLPHVEDPSLFIDFNDLT 98

  Fly   101 ---PVFSH-------------------PQSSPLDTHAAA------TASL---APPNQH--APFLS 132
               |..|.                   |:.:||.|...|      .::|   .||:..  .|..|
  Fly    99 VCPPDLSDWEQRLLDNYVEIPDLVDFLPERTPLCTDNCADFLEESNSNLRLSGPPHSEIFVPDRS 163

  Fly   133 AASDLYYAAAAAAAAAASTPTAVPGFGMDPFTMGLMEQEYARVMAEDAQLKALNSRKQRPKKFKC 197
            ::|. ..:.:|:.|.|.:.|:|:.                   |:|:|         ...:.:.|
  Fly   164 SSSP-GSSDSASPAEAVAPPSALQ-------------------MSENA---------AGERGYLC 199

  Fly   198 P--NCDVAFSNNGQLKGHIRIHTGERPFKCDVNTCGKTFTRNEELTRHKRIHTGLRPYPCSACGK 260
            .  ||:..::....||.|:|.|.||:|:.|....|...|:|::||.||||.|:|::||.|..|.|
  Fly   200 TFGNCEKIYAKPAHLKAHLRRHLGEKPYVCSWPDCVWRFSRSDELARHKRSHSGVKPYKCDYCSK 264

  Fly   261 KFGRRDHLKKHMKTHMPQERQL 282
            .|.|.|||.||.|.|   ||:|
  Fly   265 CFARSDHLTKHRKVH---ERRL 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hkb	NP_524221.1	COG5048	195..>261	CDD:227381	27/67 (40%)
		zf-C2H2	195..217	CDD:278523	7/23 (30%)
		C2H2 Zn finger	197..217	CDD:275368	7/21 (33%)
		zf-H2C2_2	210..236	CDD:290200	11/25 (44%)
		C2H2 Zn finger	225..247	CDD:275368	10/21 (48%)
		zf-H2C2_2	239..264	CDD:290200	14/24 (58%)
		C2H2 Zn finger	255..275	CDD:275368	11/19 (58%)
Klf15	NP_572185.1	zf-C2H2_8	199..278	CDD:292531	35/78 (45%)
		C2H2 Zn finger	203..221	CDD:275368	6/17 (35%)
		C2H2 Zn finger	229..251	CDD:275368	10/21 (48%)
		zf-H2C2_2	243..268	CDD:290200	14/24 (58%)
		C2H2 Zn finger	259..279	CDD:275368	11/19 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010