DRSC/TRiP Functional Genomics Resources

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Protein Alignment hkb and Sp5

DIOPT Version :9

Sequence 1:NP_524221.1 Gene:hkb / 40549 FlyBaseID:FBgn0261434 Length:297 Species:Drosophila melanogaster
Sequence 2:NP_001100022.1 Gene:Sp5 / 296510 RGDID:1308499 Length:398 Species:Rattus norvegicus


Alignment Length:338 Identity:105/338 - (31%)
Similarity:144/338 - (42%) Gaps:89/338 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 SRLFRPWDTQRQAATSAA---PR-TVKQEPEAITIKTELASSSFG--HDC----------DGDFS 61
            ||||.||.....|.:..|   |. ::...|:    ||.| ..|||  |:.          ..:||
  Rat    67 SRLFHPWTADMPAHSPGALPPPHPSLGLTPQ----KTHL-QPSFGAAHELPLTPPADPSYPYEFS 126

  Fly    62 SASSSASSSSNSSKSCYEEALNHSS-------YTRTSTP-----------LLDAAPH----PVFS 104
            ......||.:....||....:.:::       |:....|           .|..||.    |.:|
  Rat   127 PVKMLPSSMAALPASCAPAYVPYAAQAALPPGYSNLLPPPPPPPPPPTCRQLSPAPAPDDLPWWS 191

  Fly   105 HPQ------SSPLDTHAAATASLAPPNQHAPFLSAASDLYYAAAAAAAAAASTPTAVPGFGMDPF 163
            .||      ||.:...:.::|...||  |||...|:     ||||||||||    ...|..:.|.
  Rat   192 IPQSGAGPGSSGVPGTSLSSACAGPP--HAPRFPAS-----AAAAAAAAAA----LQRGLVLGPS 245

  Fly   164 TMGLMEQEYARVMAEDAQLKALNSRKQRPKKFKCPNCDVA------------------------F 204
            .....:.:.|.::...|.|.|   ..:|.::.:||||..|                        :
  Rat   246 DFAQYQSQIAALLQTKAPLAA---TARRCRRCRCPNCQAAGGAPEAEPGKKKQHVCHVPGCGKVY 307

  Fly   205 SNNGQLKGHIRIHTGERPFKCDVNTCGKTFTRNEELTRHKRIHTGLRPYPCSACGKKFGRRDHLK 269
            .....||.|:|.|||||||.|:...|||:|||::||.||.|.|||.:.:.|..|||:|.|.|||.
  Rat   308 GKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRFACPECGKRFMRSDHLA 372

  Fly   270 KHMKTHMPQERQL 282
            ||:|||  |.::|
  Rat   373 KHVKTH--QNKKL 383

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hkbNP_524221.1 COG5048 195..>261 CDD:227381 34/89 (38%)
zf-C2H2 195..217 CDD:278523 9/45 (20%)
C2H2 Zn finger 197..217 CDD:275368 9/43 (21%)
zf-H2C2_2 210..236 CDD:290200 16/25 (64%)
C2H2 Zn finger 225..247 CDD:275368 12/21 (57%)
zf-H2C2_2 239..264 CDD:290200 13/24 (54%)
C2H2 Zn finger 255..275 CDD:275368 12/19 (63%)
Sp5NP_001100022.1 SP1-4_N 31..>47 CDD:425404
SP5_N 106..297 CDD:412096 48/204 (24%)
C2H2 Zn finger 301..320 CDD:275368 4/18 (22%)
COG5048 <311..384 CDD:227381 42/75 (56%)
C2H2 Zn finger 328..350 CDD:275368 12/21 (57%)
zf-H2C2_2 342..365 CDD:404364 12/22 (55%)
C2H2 Zn finger 358..378 CDD:275368 12/19 (63%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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