DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hkb and Sp4

DIOPT Version :9

Sequence 1:	NP_524221.1	Gene:	hkb / 40549	FlyBaseID:	FBgn0261434	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_036893.1	Gene:	Sp4 / 25162	RGDID:	3741	Length:	783	Species:	Rattus norvegicus

Alignment Length:	333	Identity:	82/333 - (24%)
Similarity:	122/333 - (36%)	Gaps:	89/333 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 PPQTYSRLFRPWDTQRQAATSAAPRTVKQE-----------PEAITIKTELASSSFGHDCDGDFS 61
            |||::           |..:....:|::|:           |..:.|:....:.|      |..|
  Rat   420 PPQSF-----------QLQSGQTIQTIQQQPLQNVQLQAVNPTQVLIRAPTLTPS------GQIS 467

  Fly    62 SASSSASSSSNSSKSCYEEALNHSSYTRT------STPLLDAAPHPVFSHPQSSPLDTHAAATAS 120
            ..:....:..:.|....:.|......|.|      .|.|...||..|    ..:|:..:.|..||
  Rat   468 WQTVQVQNIQSLSNLQVQNAGLSQQLTITPVSSSGGTTLAQIAPVAV----AGAPITLNTAQLAS 528

  Fly   121 LAPPN----------------QHAP--FLSAASDLYYAAAAAAAAAASTPTAVPGFGMDPFTMGL 167
            :  ||                |..|  ..|.|.............|...|..|...|:...|:|.
  Rat   529 V--PNLQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANATIGA 591

  Fly   168 ME-QEYARVMAEDAQLKALNSRKQRPKKFK-----CPN------------------------CDV 202
            :. .:..:|..:..| :..::..|..|:.:     |||                        |..
  Rat   592 VSPDQLTQVHLQQGQ-QTSDAEVQPGKRLRRVACSCPNCREGEGRGSSEPGKKKQHVCHIEGCGK 655

  Fly   203 AFSNNGQLKGHIRIHTGERPFKCDVNTCGKTFTRNEELTRHKRIHTGLRPYPCSACGKKFGRRDH 267
            .:.....|:.|:|.|||||||.|:...|||.|||::||.||:|.|||.:.:.|..|.|:|.|.||
  Rat   656 VYGKTSHLRAHLRWHTGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKRFECPECSKRFMRSDH 720

  Fly   268 LKKHMKTH 275
            |.||:|||
  Rat   721 LSKHVKTH 728

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hkb	NP_524221.1	COG5048	195..>261	CDD:227381	31/94 (33%)
		zf-C2H2	195..217	CDD:278523	7/50 (14%)
		C2H2 Zn finger	197..217	CDD:275368	7/43 (16%)
		zf-H2C2_2	210..236	CDD:290200	15/25 (60%)
		C2H2 Zn finger	225..247	CDD:275368	12/21 (57%)
		zf-H2C2_2	239..264	CDD:290200	12/24 (50%)
		C2H2 Zn finger	255..275	CDD:275368	11/19 (58%)
Sp4	NP_036893.1	C2H2 Zn finger	648..670	CDD:275368	4/21 (19%)
		COG5048	<661..732	CDD:227381	38/68 (56%)
		zf-H2C2_2	662..689	CDD:290200	15/26 (58%)
		C2H2 Zn finger	678..700	CDD:275368	12/21 (57%)
		zf-H2C2_2	692..715	CDD:290200	11/22 (50%)
		zf-C2H2	706..728	CDD:278523	11/21 (52%)
		C2H2 Zn finger	708..728	CDD:275368	11/19 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910