DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment hkb and Klf8

DIOPT Version :10

Sequence 1:NP_524221.1 Gene:hkb / 40549 FlyBaseID:FBgn0261434 Length:297 Species:Drosophila melanogaster
Sequence 2:XP_006528923.2 Gene:Klf8 / 245671 MGIID:2442430 Length:457 Species:Mus musculus


Alignment Length:303 Identity:79/303 - (26%)
Similarity:122/303 - (40%) Gaps:67/303 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 INLHPPQTYSRLFRPWDTQRQAATSAAPRTVKQEPEAITIKTELASSSFGHDCDGDFSSASSSAS 68
            ::.|.|:.      |............|......|:||.:.|         ..|...|:|..:..
Mouse   188 LSFHKPKA------PLQPASMLQAPIRPPKPPTAPQAIMVPT---------SADTVTSAAIPTVL 237

  Fly    69 SSSN---SSKSCYEEALNHSSYTRTSTPL------LDAAPHPVFSHPQ---SSPLDTHAAA---- 117
            :..:   ||:....:.:.|..:|..|..|      |...|..|.|.|.   |.|.|...||    
Mouse   238 TPGSILASSQGTGGQPILHVIHTIPSVSLPNKMSGLKTIPLVVQSLPMVYTSLPTDGSPAAITVP 302

  Fly   118 ---------------TASLAPPNQHAPFLSAASDLYYAAAAAAAAAASTPTAVPGFGMDPFTMGL 167
                           .||:.|       |...||   :..:|..:.:|...::.||..:|.||..
Mouse   303 LIGGDGKSAGSVKVDPASMCP-------LEFPSD---SDESAIESGSSALQSLQGFHHEPATMVH 357

  Fly   168 MEQEYARVMAEDAQLKALNSRKQRPKKFKCPNCDVAFSNNGQLKGHIRIHTGERPFKCDVNTCGK 232
            |:.|           ::|:.:::|..:.....|...::.:..||.|.||||||:|:||..:.|..
Mouse   358 MQGE-----------ESLDLKRRRIHQCDFAGCSKVYTKSSHLKAHRRIHTGEKPYKCTWDGCSW 411

  Fly   233 TFTRNEELTRHKRIHTGLRPYPCSACGKKFGRRDHLKKHMKTH 275
            .|.|::|||||.|.|||::|:.|:.|.:.|.|.|||..|.:.|
Mouse   412 KFARSDELTRHFRKHTGIKPFRCTDCNRSFSRSDHLSLHRRRH 454

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
hkbNP_524221.1 COG5048 195..>261 CDD:227381 28/65 (43%)
C2H2 Zn finger 197..217 CDD:275368 5/19 (26%)
C2H2 Zn finger 225..247 CDD:275368 10/21 (48%)
zf-C2H2 253..275 CDD:395048 8/21 (38%)
C2H2 Zn finger 255..275 CDD:275368 8/19 (42%)
Klf8XP_006528923.2 KLF8_N 147..314 CDD:410607 27/140 (19%)
COG5048 370..>440 CDD:227381 29/69 (42%)
C2H2 Zn finger 374..396 CDD:275368 5/21 (24%)
C2H2 Zn finger 404..426 CDD:275368 10/21 (48%)
zf-C2H2 432..454 CDD:395048 8/21 (38%)
C2H2 Zn finger 434..454 CDD:275368 8/19 (42%)

Return to query results.
Submit another query.