DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment hkb and sptf-2

DIOPT Version :9

Sequence 1:	NP_524221.1	Gene:	hkb / 40549	FlyBaseID:	FBgn0261434	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_495833.1	Gene:	sptf-2 / 188733	WormBaseID:	WBGene00011926	Length:	166	Species:	Caenorhabditis elegans

Alignment Length:	178	Identity:	46/178 - (25%)
Similarity:	77/178 - (43%)	Gaps:	46/178 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 AATASLAPPNQHAPFLSAASDLYYAAAAAAAAAASTPTAVPGFGMDPFTMGLMEQEYARVMAEDA 180
            |||....|...|..:..:...:....:.|:.:|:|:.:::          |..|
Worm     4 AATKFFRPWESHGSYHHSLPSISPPDSPASTSASSSSSSI----------GANE----------- 47

  Fly   181 QLKALNSRKQRPKKFKCPNCDV---------------------AFSNNGQLKGHIRIHTGERPFK 224
                |.:::::.::..||||..                     .:.....|:.|:|.|||:|||.
Worm    48 ----LTTKRRKCERCTCPNCKAIKHGDRGSQHTHLCSVPGCGKTYKKTSHLRAHLRKHTGDRPFV 108

  Fly   225 CDVNTCGKTFTRNEELTRHKRIHTGLRPYPCSACGKKFGRRDHLKKHM 272
            ||...|||.|.|:::|.||||.||....:.|..|.::|.|.|||::|:
Worm   109 CDWFDCGKRFDRSDQLIRHKRTHTKEYRFACKFCIRQFSRSDHLQQHL 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hkb	NP_524221.1	COG5048	195..>261	CDD:227381	29/86 (34%)
		zf-C2H2	195..217	CDD:278523	7/42 (17%)
		C2H2 Zn finger	197..217	CDD:275368	7/40 (18%)
		zf-H2C2_2	210..236	CDD:290200	15/25 (60%)
		C2H2 Zn finger	225..247	CDD:275368	12/21 (57%)
		zf-H2C2_2	239..264	CDD:290200	10/24 (42%)
		C2H2 Zn finger	255..275	CDD:275368	8/18 (44%)
sptf-2	NP_495833.1	COG5048	<75..156	CDD:227381	30/80 (38%)
		C2H2 Zn finger	82..101	CDD:275368	3/18 (17%)
		C2H2 Zn finger	109..131	CDD:275368	12/21 (57%)
		C2H2 Zn finger	139..156	CDD:275368	7/16 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1591573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920