DRSC/TRiP Functional Genomics Resources

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Protein Alignment Skp2 and SKIP2

DIOPT Version :9

Sequence 1:NP_730815.2 Gene:Skp2 / 40548 FlyBaseID:FBgn0037236 Length:559 Species:Drosophila melanogaster
Sequence 2:NP_569047.1 Gene:SKIP2 / 836860 AraportID:AT5G67250 Length:527 Species:Arabidopsis thaliana


Alignment Length:412 Identity:84/412 - (20%)
Similarity:146/412 - (35%) Gaps:120/412 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   242 LSDEILLDIFKWLPKKTLLRMATVCRRF--------NRCS---RDE------TLWTRLD----LG 285
            |.||.|..:|::|......|.:.||:|:        :|.|   :||      :::.|.|    |.
plant    46 LPDECLAHVFQFLGAGDRKRCSLVCKRWLLVDGQSRHRLSLDAKDEISSFLTSMFNRFDSVTKLA 110

  Fly   286 LRTIRPG------ALEQIVRRGVLVIRLAQTSIQE------PAFAPYTEVFRTRLQYLDLSMASI 338
            ||..|..      ||..|..|.:.:.|:.....:|      ..||...:    .|:.|.:...:.
plant   111 LRCDRKSVSLSDEALAMISVRCLNLTRVKLRGCREITDLGMEDFAKNCK----NLKKLSVGSCNF 171

  Fly   339 TRSSLLTLLSHCRQLKKISL----------ENIELDDD--------ICAE-----------IAKN 374
            ....:..:|.||:.|:::|:          |.|.|.||        ||.:           :|..
plant   172 GAKGVNAMLEHCKLLEELSVKRLRGIHEAAELIHLPDDASSSSLRSICLKELVNGQVFEPLLATT 236

  Fly   375 EALEAVNLTMASGLTSNSVRLMMESLTSLSSLNISWTDLSADAVTAL-------VTHI--SPN-- 428
            ..|:.:.:....|.....::::....:|||.:::....:|...::|:       ..||  :|.  
plant   237 RTLKTLKIIRCLGDWDKVLQMIANGKSSLSEIHLERLQVSDIGLSAISKCSNVETLHIVKTPECS 301

  Fly   429 -------------LIRLNIAGCR-RVLFDSHVATLQKRCPQLLELDLSDCNSLTPTVITAIMKFK 479
                         |.:|:|.|.| ..:.|..:.::.|.|..|.||.|...|:...::.......:
plant   302 NFGLIYVAERCKLLRKLHIDGWRTNRIGDEGLLSVAKHCLNLQELVLIGVNATHMSLAAIASNCE 366

  Fly   480 MLEYLSVSRCYLIPAT-------------KFIELKSMPSLTYLDIFGMLSDTAMEVLEKQLPKMG 531
            .||.|::.....|..|             ||. :|..|          :||..:|.|     .:|
plant   367 KLERLALCGSGTIGDTEIACIARKCGALRKFC-IKGCP----------VSDRGIEAL-----AVG 415

  Fly   532 INKFIHSSVSRPTVGTRRTSIW 553
            ....:...|.:..|.|.....|
plant   416 CPNLVKLKVKKCKVVTGEIGDW 437

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Skp2NP_730815.2 F-box-like 239..284 CDD:289689 16/62 (26%)
leucine-rich repeat 302..327 CDD:275381 4/30 (13%)
AMN1 309..480 CDD:187754 41/230 (18%)
leucine-rich repeat 328..352 CDD:275381 5/23 (22%)
leucine-rich repeat 353..376 CDD:275381 10/51 (20%)
leucine-rich repeat 377..402 CDD:275381 2/24 (8%)
leucine-rich repeat 403..428 CDD:275381 6/33 (18%)
leucine-rich repeat 429..455 CDD:275381 8/26 (31%)
leucine-rich repeat 456..480 CDD:275381 5/23 (22%)
leucine-rich repeat 481..500 CDD:275381 7/31 (23%)
leucine-rich repeat 506..529 CDD:275381 4/22 (18%)
SKIP2NP_569047.1 F-box-like 45..>73 CDD:403981 9/26 (35%)
AMN1 82..295 CDD:187754 41/216 (19%)
leucine-rich repeat 106..128 CDD:275381 6/21 (29%)
leucine-rich repeat 135..160 CDD:275381 4/28 (14%)
leucine-rich repeat 161..185 CDD:275381 5/23 (22%)
leucine-rich repeat 239..264 CDD:275381 2/24 (8%)
leucine-rich repeat 265..288 CDD:275381 4/22 (18%)
leucine-rich repeat 289..314 CDD:275381 3/24 (13%)
AMN1 <311..>416 CDD:187754 26/120 (22%)
leucine-rich repeat 315..342 CDD:275381 8/26 (31%)
leucine-rich repeat 343..367 CDD:275381 5/23 (22%)
leucine-rich repeat 368..393 CDD:275381 5/24 (21%)
leucine-rich repeat 394..418 CDD:275381 9/39 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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