DRSC/TRiP Functional Genomics Resources

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Protein Alignment Skp2 and TIR1

DIOPT Version :10

Sequence 1:NP_730815.2 Gene:Skp2 / 40548 FlyBaseID:FBgn0037236 Length:559 Species:Drosophila melanogaster
Sequence 2:NP_567135.1 Gene:TIR1 / 825473 AraportID:AT3G62980 Length:594 Species:Arabidopsis thaliana


Alignment Length:365 Identity:75/365 - (20%)
Similarity:126/365 - (34%) Gaps:127/365 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   244 DEILLDIFKWLP-KKTLLRMATVCRRFNRCSRDETLWTRLDLGLRTIRPGALEQIVRRGVLVIRL 307
            :|:|..:|.::. .|....::.||:.:....|    |.|..:.:......:...::||...|   
plant    11 EEVLEHVFSFIQLDKDRNSVSLVCKSWYEIER----WCRRKVFIGNCYAVSPATVIRRFPKV--- 68

  Fly   308 AQTSIQ---EPAFA--------------PYTEVFRTRLQYLD----------------------- 332
              .|::   :|.||              |:.|...:...:|:                       
plant    69 --RSVELKGKPHFADFNLVPDGWGGYVYPWIEAMSSSYTWLEEIRLKRMVVTDDCLELIAKSFKN 131

  Fly   333 ------LSMASITRSSLLTLLSHCRQLKKISLENIELDDDICAEIAKNEALEAVNLTMASGLTSN 391
                  .|....:...|..:.:.||.||::.|...::||                      ::.:
plant   132 FKVLVLSSCEGFSTDGLAAIAATCRNLKELDLRESDVDD----------------------VSGH 174

  Fly   392 SVRLMMESLTSLSSLNISW--TDLSADAVTALVTHISPNL--IRLNIAGCRRVLFDSHVATLQKR 452
            .:....::.|||.|||||.  :::|..|:..|||. .|||  ::||    |.|..:. :|||.:|
plant   175 WLSHFPDTYTSLVSLNISCLASEVSFSALERLVTR-CPNLKSLKLN----RAVPLEK-LATLLQR 233

  Fly   453 CPQLLELD-------------------LSDCNSL---------TPTVITAI------MKFKMLEY 483
            .|||.||.                   ||.|..|         .|..:.|:      :....|.|
plant   234 APQLEELGTGGYTAEVRPDVYSGLSVALSGCKELRCLSGFWDAVPAYLPAVYSVCSRLTTLNLSY 298

  Fly   484 LSVSRCYLIPATKFIELKSMPSLTYLDIFGMLSDTAMEVL 523
            .:|....|:..     |...|.|..|.:...:.|..:|||
plant   299 ATVQSYDLVKL-----LCQCPKLQRLWVLDYIEDAGLEVL 333

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Skp2NP_730815.2 F-box_DmSKP2-like 239..281 CDD:438920 8/37 (22%)
leucine-rich repeat 302..327 CDD:275381 7/41 (17%)
AMN1 309..480 CDD:187754 51/254 (20%)
leucine-rich repeat 328..352 CDD:275381 4/52 (8%)
leucine-rich repeat 353..376 CDD:275381 5/22 (23%)
leucine-rich repeat 377..402 CDD:275381 0/24 (0%)
leucine-rich repeat 403..428 CDD:275381 11/26 (42%)
leucine-rich repeat 429..455 CDD:275381 9/27 (33%)
leucine-rich repeat 456..480 CDD:275381 9/57 (16%)
leucine-rich repeat 481..500 CDD:275381 4/18 (22%)
leucine-rich repeat 506..529 CDD:275381 6/18 (33%)
TIR1NP_567135.1 F-box_5 8..47 CDD:436553 9/39 (23%)
Transp_inhibit 66..112 CDD:465867 8/50 (16%)
leucine-rich repeat 107..131 CDD:275381 1/23 (4%)
LRR <127..>319 CDD:443914 51/224 (23%)
leucine-rich repeat 132..157 CDD:275381 3/24 (13%)
leucine-rich repeat 158..212 CDD:275381 18/76 (24%)
leucine-rich repeat 213..286 CDD:275381 20/77 (26%)
AMN1 286..>400 CDD:187754 12/53 (23%)
leucine-rich repeat 291..315 CDD:275381 5/28 (18%)
leucine-rich repeat 316..339 CDD:275381 6/18 (33%)
leucine-rich repeat 340..373 CDD:275381
leucine-rich repeat 374..398 CDD:275381
leucine-rich repeat 399..433 CDD:275381
leucine-rich repeat 434..457 CDD:275381
leucine-rich repeat 458..482 CDD:275381
leucine-rich repeat 483..507 CDD:275381
Blue background indicates that the domain is not in the aligned region.

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