Protein Alignment Skp2 and Fbxl3

DIOPT Version :10

• Sequence 1: NP_730815.2
• Gene: Skp2 / 40548
• FlyBaseID: FBgn0037236
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_056637.1
• Gene: Fbxl3 / 50789
• MGIID: 1354702
• Length: 428
• Species: Mus musculus
• Alignment Length: 306
• Identity: 63/306 - (20%)
• Similarity: 116/306 - (37%)
• Gaps: 70/306 - (22%)

  Fly   242 LSDEILLDIFKWLPKKTLLRMATVCRRFNRCSRDETLWTRLDLG--------LRTIRPGALEQIV 298
            |..:|:|.:||:||.......:.|||.:|:......||...:..        |:...|..::||:
Mouse    39 LLQDIVLHVFKYLPLLDRAHASQVCRNWNQVFHMPDLWRCFEFELNQPATSYLKATHPELIKQII 103

  Fly   299 RRGVLVIRLAQTSIQEPAFAPYTEVFRTRLQYLDLSMASITRSS-----LLTLLSHCRQLKKISL 358
            :|                       ....|||:...:.|...|:     :|:.|.:| .||.:.|
Mouse   104 KR-----------------------HSNHLQYVSFKVDSSKESAEAACDILSQLVNC-SLKTLGL 144

  Fly   359 ENIELDDDICAEIAKNEALEAVNLTMASGLTSNSVRLMMESLTSLSSLNISWTDLSADAVTALVT 423
              |........::.|:..:.|:.:...:.             .|||||.|..|.:...::..||.
Mouse   145 --ISTARPSFMDLPKSHFISALTVVFVNS-------------KSLSSLKIDDTPVDDPSLKVLVA 194

  Fly   424 HISPNLIRLNIAGCRRVLFDSHVATLQKRCPQLLELDLSDCNSLTPTVITAIM--KFKMLEYLSV 486
            :.|..|..|.::.|..| ..:.:..:..:|..|.||.| :.:.|:..::.|:.  |...||:|.:
Mouse   195 NNSDTLKLLKMSSCPHV-SPAGILCVADQCHGLRELAL-NYHLLSDELLLALSSEKHVRLEHLRI 257

  Fly   487 SRCYLIPATKFIELKSMPSLTYLDIFGMLSDTAMEVLEKQLPKMGI 532
            .           .:...|..|:   |..:..::.:...|..||:.:
Mouse   258 D-----------VVSENPGQTH---FHTIQKSSWDAFIKHSPKVNL 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Skp2	NP_730815.2	F-box_DmSKP2-like	239..281	CDD:438920	13/38 (34%)
		leucine-rich repeat	302..327	CDD:275381	0/24 (0%)
		AMN1	309..480	CDD:187754	36/177 (20%)
		leucine-rich repeat	328..352	CDD:275381	8/28 (29%)
		leucine-rich repeat	353..376	CDD:275381	5/22 (23%)
		leucine-rich repeat	377..402	CDD:275381	1/24 (4%)
		leucine-rich repeat	403..428	CDD:275381	9/24 (38%)
		leucine-rich repeat	429..455	CDD:275381	5/25 (20%)
		leucine-rich repeat	456..480	CDD:275381	7/25 (28%)
		leucine-rich repeat	481..500	CDD:275381	3/18 (17%)
		leucine-rich repeat	506..529	CDD:275381	3/22 (14%)
Fbxl3	NP_056637.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..33
		F-box_FBXL3	34..76	CDD:438949	11/36 (31%)
		FBXL3_LRR	79..428	CDD:467832	50/266 (19%)
		LRR 1	119..146		8/29 (28%)
		leucine-rich repeat	174..199	CDD:275381	9/24 (38%)
		LRR 2	181..207		6/25 (24%)
		leucine-rich repeat	200..225	CDD:275381	5/25 (20%)
		LRR 3	208..233		7/26 (27%)
		LRR 4	234..259		6/35 (17%)
		leucine-rich repeat	252..286	CDD:275381	7/47 (15%)
		leucine-rich repeat	287..333	CDD:275381	0/3 (0%)
		LRR 5	316..341
		leucine-rich repeat	334..360	CDD:275381
		LRR 6	343..368
		leucine-rich repeat	361..383	CDD:275381
		LRR 7	369..394