DRSC/TRiP Functional Genomics Resources

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Protein Alignment Skp2 and gadr-5

DIOPT Version :9

Sequence 1:NP_730815.2 Gene:Skp2 / 40548 FlyBaseID:FBgn0037236 Length:559 Species:Drosophila melanogaster
Sequence 2:NP_001252264.2 Gene:gadr-5 / 4927064 WormBaseID:WBGene00045058 Length:915 Species:Caenorhabditis elegans


Alignment Length:327 Identity:82/327 - (25%)
Similarity:125/327 - (38%) Gaps:88/327 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   208 TNITTRIVAADSFFVFRTPAMSAHINSGINYFERLSDEILLDIFKWLPKKTLLRMATVCRRFNRC 272
            ||....|.||.         ::.||..| :|.:.       :||:.|..|:              
 Worm   225 TNSLANIAAAQ---------IARHIEDG-HYKDP-------NIFQELDTKS-------------- 258

  Fly   273 SRDETLWTRLDLGLRTIRPGALEQIVRRGVLVIRLAQTSIQEPAFAPYTEVFRTRLQYLDLSMAS 337
              .|.::::|.|    :.|.|.:.|.:         .|.|||      :.|...|:........:
 Worm   259 --HEAIFSKLLL----LNPKAYKFIAK---------ATQIQE------SVVIGKRVHAQHYYARN 302

  Fly   338 ITRSSLLTLLSHCRQLKKISLENIELDDDICAEIAKNEALEAVNLTMASGLTSNSVRLMMESLTS 402
            |...:.||.:.:.:.|.||.    .||...|                .|.||...|||:...|.|
 Worm   303 IDIMTSLTSVLYGKSLAKIH----SLDIGEC----------------RSQLTPGWVRLIGTMLPS 347

  Fly   403 LSSLNISWTDLSADAVTALVTHISPNLIRLNIAGCRRVLFDSHVATLQ--KRCPQLLELDLSDCN 465
            |.||:||...||.:..:.|..... ||.:|||:       |:.|..||  .:...|..|.:.:..
 Worm   348 LQSLDISNKPLSKEDFSQLCNFFQ-NLQKLNIS-------DTCVKKLQGISKLKNLKVLSMRNLQ 404

  Fly   466 SLTPTVITAIMKFKMLEYLSVSR----CYLIPATKFIELKS-MPSLTYLDIFGM-LSDTAMEVLE 524
            ..|.|.:..:.|.|.|..|.|||    ..:....:|:|..: :||||:||..|. ::...::.||
 Worm   405 FRTATDMLDLFKLKGLVALDVSRDIAKANIKTIRQFVECGNVLPSLTFLDASGTDINQDLLDSLE 469

  Fly   525 KQ 526
            .|
 Worm   470 YQ 471

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Skp2NP_730815.2 F-box-like 239..284 CDD:289689 6/44 (14%)
leucine-rich repeat 302..327 CDD:275381 5/24 (21%)
AMN1 309..480 CDD:187754 45/172 (26%)
leucine-rich repeat 328..352 CDD:275381 3/23 (13%)
leucine-rich repeat 353..376 CDD:275381 6/22 (27%)
leucine-rich repeat 377..402 CDD:275381 7/24 (29%)
leucine-rich repeat 403..428 CDD:275381 8/24 (33%)
leucine-rich repeat 429..455 CDD:275381 8/27 (30%)
leucine-rich repeat 456..480 CDD:275381 5/23 (22%)
leucine-rich repeat 481..500 CDD:275381 6/22 (27%)
leucine-rich repeat 506..529 CDD:275381 8/22 (36%)
gadr-5NP_001252264.2 MFS <15..201 CDD:119392
LRR <311..514 CDD:227223 54/189 (29%)
leucine-rich repeat 348..372 CDD:275382 8/24 (33%)
LRR_4 371..>402 CDD:289563 11/38 (29%)
leucine-rich repeat 373..396 CDD:275382 8/29 (28%)
leucine-rich repeat 397..419 CDD:275380 4/21 (19%)
leucine-rich repeat 420..449 CDD:275380 7/28 (25%)
leucine-rich repeat 450..473 CDD:275380 8/22 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C160162730
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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