Protein Alignment Skp2 and Fbxl22

DIOPT Version :10

• Sequence 1: NP_730815.2
• Gene: Skp2 / 40548
• FlyBaseID: FBgn0037236
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001102239.1
• Gene: Fbxl22 / 363083
• RGDID: 1311830
• Length: 236
• Species: Rattus norvegicus
• Alignment Length: 311
• Identity: 58/311 - (18%)
• Similarity: 104/311 - (33%)
• Gaps: 89/311 - (28%)

  Fly   238 YFERLSDEILLDIFKWLPKKTLLRMATVCRRFNRCSRDETLWTRLDLGLRTIRPGALEQIVRRGV 302
            :..:|:.|.||.:|.:|.|.:...::..|.:......|.|||:.|.
  Rat     2 HITQLNRECLLRLFSFLDKDSRKSLSRTCSQLRDVFEDPTLWSLLH------------------- 47

  Fly   303 LVIRLAQTSIQEPAFAPYTEVFRTRLQYLDLSMASITRSSLLTLLSHCRQLKKISLENIELDDDI 367
                          |...||          |...:...|..|..||.|....::.:.:||
  Rat    48 --------------FHSLTE----------LKKDNFRLSPALRSLSICWHSSRVQVCSIE----- 83

  Fly   368 CAEIAKNEALEAVNLTMASGLTSNSVRLMMESLTSLSSLNISWTDLSADAVTALVTHISPNLIRL 432
                      :.:.......:.|....|:.:.|..                   |.:..|||..:
  Rat    84 ----------DWLKSAFQRSICSQHENLVNDFLLQ-------------------VCNRCPNLASV 119

  Fly   433 NIAGCRRVLFDSHVATLQKRCPQLLELDLSDCNSLTPTVITAIMKF-KMLEYLSVSRCYLIPATK 496
            .::||..|. |..:|.|...||:|..|.|.:|..:|...:.|:... :.|:...|..|..:.|..
  Rat   120 TLSGCGHVT-DDCLARLLLGCPRLRALRLENCARVTNRTLAAVAAHGRALQTFHVDFCRNVSAAG 183

  Fly   497 FIELK-SMPSLTYLDIFGMLSDTAMEVLEKQLPKMGINKFIHSSVSRPTVG 546
            .:.|: :.|:|.      :.::.:..::..|.|:...:.   :||..|..|
  Rat   184 LLRLRAACPNLI------LSAEHSAAMIPDQPPRARASP---ASVFSPAPG 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Skp2	NP_730815.2	F-box_DmSKP2-like	239..281	CDD:438920	12/41 (29%)
		leucine-rich repeat	302..327	CDD:275381	3/24 (13%)
		AMN1	309..480	CDD:187754	32/171 (19%)
		leucine-rich repeat	328..352	CDD:275381	6/23 (26%)
		leucine-rich repeat	353..376	CDD:275381	2/22 (9%)
		leucine-rich repeat	377..402	CDD:275381	3/24 (13%)
		leucine-rich repeat	403..428	CDD:275381	1/24 (4%)
		leucine-rich repeat	429..455	CDD:275381	8/25 (32%)
		leucine-rich repeat	456..480	CDD:275381	6/24 (25%)
		leucine-rich repeat	481..500	CDD:275381	4/18 (22%)
		leucine-rich repeat	506..529	CDD:275381	2/22 (9%)
Fbxl22	NP_001102239.1	F-box_FBXL22	3..45	CDD:438901	12/41 (29%)
		AMN1	44..>191	CDD:187754	38/224 (17%)
		leucine-rich repeat	116..141	CDD:275381	8/25 (32%)
		leucine-rich repeat	142..167	CDD:275381	6/24 (25%)
		leucine-rich repeat	168..193	CDD:275381	5/24 (21%)