DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Skp2 and CG9003

DIOPT Version :9

Sequence 1:NP_730815.2 Gene:Skp2 / 40548 FlyBaseID:FBgn0037236 Length:559 Species:Drosophila melanogaster
Sequence 2:NP_001097271.1 Gene:CG9003 / 36244 FlyBaseID:FBgn0033639 Length:651 Species:Drosophila melanogaster


Alignment Length:565 Identity:126/565 - (22%)
Similarity:225/565 - (39%) Gaps:106/565 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 SSRKHRGSENMENLCPVTRKRSTNKNHVSVVGALVSTTKSSHYEHPSSPSALTFEALEEMGIGML 66
            ||.......::|.|||                             ||..|:::..|......|..
  Fly    33 SSNSGGAGGSIELLCP-----------------------------PSGSSSISGSASFSSNSGAS 68

  Fly    67 -DSEESSSSALSAIALAVSATSDDNSNETTPCASVSRMAHQLQHTQRLSLGSTGDITLDSPAVED 130
             .|.::.|:|:|      |||...|:|......|:....:...:|::.|.||.        :.:.
  Fly    69 GSSSQTHSTAVS------SATDRSNNNGNNHNPSLQLNGNGGSNTRQHSSGSN--------SRQH 119

  Fly   131 SLSMSRQSAEKLQILAQAKRSSLGSEGSGNSNSPSKRLRNPLAAVTCNNQIDGTAS--LNFQPST 193
            |.|.|..::..   ::....||..|..:.|:|:.|..:.:...:....:...|:|:  :|..|:.
  Fly   120 SSSSSNSNSSN---ISPPPSSSSSSRSNNNNNNHSSNIISGFCSTIWRSATFGSATPVINPLPAV 181

  Fly   194 SRLAQVRQAKKPS---TTNITTRIVAADSFFVFRTPAMSAHINS-------------GINYFERL 242
            |...::.::...|   :::.|..:..||.   .|..|.||...|             .....::|
  Fly   182 SINPKIMESSSDSCSLSSSTTPDVGLADQ---QRNMAGSAQDQSEDQSQTFLGATELDDELIKQL 243

  Fly   243 SDEILLDIFKWLPKKTLLRMATVCRRFNRCSRDETLWTRLDL--GLRTIRPGALEQIVRRGVLVI 305
            ..|:||.:|.:|...:|.|.|.||:.:|..:.|.:.|.:::|  ..|.|....:|.|.:|     
  Fly   244 PKEVLLRVFSYLDVVSLCRCAQVCKYWNVLALDGSSWQKINLFDFQRDIEGPVIENISQR----- 303

  Fly   306 RLAQTSIQEPAFAPYTEVFRTRLQYLDL-SMASITRSSLLTLLSHCRQLKKISLENIELDDDICA 369
                              .|..|:.|.| ...|:...|:.||.:||..::.:.|.:.:...||..
  Fly   304 ------------------CRGFLKSLSLRGCQSVGDQSVRTLANHCHNIEHLDLSDCKKITDIST 350

  Fly   370 EIAKN--EALEAVNLTMASGLTSNSVRLMMESLTSLSSLNISWTDL-SADAVTALVTHISPNLIR 431
            :....  ..|.|:||...|.:|.||::.:.:...:|..:|:||..| |.:.|.||... ...|.:
  Fly   351 QSISRYCSKLTAINLHSCSNITDNSLKYLSDGCPNLMEINVSWCHLISENGVEALARG-CVKLRK 414

  Fly   432 LNIAGCRRVLFDSHVATLQKRCPQLLELDLSDCNSLTPTVITAI-MKFKMLEYLSVSRCYLIPAT 495
            .:..||::: .|:.:..|.|.||.|:.|:|..|.::|.:.|..: .....|:.|.||:|..:...
  Fly   415 FSSKGCKQI-NDNAIMCLAKYCPDLMVLNLHSCETITDSSIRQLAANCHKLQKLCVSKCADLTDL 478

  Fly   496 KFIELKSMPS-LTYLDIFGM--LSDTAMEVLE---KQLPKMGINK 534
            ..:.|..... |..|::.|.  .:|...:.|.   |.|.:|.:.:
  Fly   479 TLLSLSQHNHLLNTLEVSGCRNFTDIGFQALGRNCKYLERMDLEE 523

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Skp2NP_730815.2 F-box-like 239..284 CDD:289689 14/44 (32%)
leucine-rich repeat 302..327 CDD:275381 1/24 (4%)
AMN1 309..480 CDD:187754 44/175 (25%)
leucine-rich repeat 328..352 CDD:275381 9/24 (38%)
leucine-rich repeat 353..376 CDD:275381 3/24 (13%)
leucine-rich repeat 377..402 CDD:275381 8/24 (33%)
leucine-rich repeat 403..428 CDD:275381 9/25 (36%)
leucine-rich repeat 429..455 CDD:275381 7/25 (28%)
leucine-rich repeat 456..480 CDD:275381 6/24 (25%)
leucine-rich repeat 481..500 CDD:275381 5/18 (28%)
leucine-rich repeat 506..529 CDD:275381 7/27 (26%)
CG9003NP_001097271.1 F-box-like 240..285 CDD:289689 14/44 (32%)
leucine-rich repeat 280..307 CDD:275381 8/49 (16%)
AMN1 <308..453 CDD:187754 42/146 (29%)
leucine-rich repeat 308..327 CDD:275381 5/18 (28%)
leucine-rich repeat 334..359 CDD:275381 3/24 (13%)
leucine-rich repeat 360..385 CDD:275381 8/24 (33%)
leucine-rich repeat 386..411 CDD:275381 9/25 (36%)
AMN1 <409..586 CDD:187754 28/116 (24%)
leucine-rich repeat 412..437 CDD:275381 7/25 (28%)
leucine-rich repeat 438..463 CDD:275381 6/24 (25%)
leucine-rich repeat 464..515 CDD:275381 11/50 (22%)
leucine-rich repeat 516..541 CDD:275381 2/8 (25%)
leucine-rich repeat 542..561 CDD:275381
leucine-rich repeat 571..595 CDD:275381
leucine-rich repeat 596..621 CDD:275381
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45457978
Domainoid 1 1.000 42 1.000 Domainoid score I3206
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.840

Return to query results.
Submit another query.