DRSC/TRiP Functional Genomics Resources

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Protein Alignment Skp2 and CG9316

DIOPT Version :9

Sequence 1:NP_730815.2 Gene:Skp2 / 40548 FlyBaseID:FBgn0037236 Length:559 Species:Drosophila melanogaster
Sequence 2:NP_610051.2 Gene:CG9316 / 35333 FlyBaseID:FBgn0032878 Length:448 Species:Drosophila melanogaster


Alignment Length:372 Identity:65/372 - (17%)
Similarity:124/372 - (33%) Gaps:148/372 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly   242 LSDEILLDIFKWLPK---KTLLRMATVCRRFNRCSRDETLWTRLD---LGLRTIRPGALEQIVR- 299
            |.::|:..:.::||:   |.||  |.|..:|......   |.|:.   |.:.::....|.|::| 
  Fly    45 LPEDIIRLVLEFLPRITDKVLL--ACVAPKFRAAFEG---WARVQRNALDMVSLETVPLPQLIRF 104

  Fly   300 ---RG--VLVIRLAQTSIQ-EPAFAPYTEVFRTRLQYLDLSMAS--ITRSSLLTLLSHCRQLKKI 356
               .|  :.|:::...|.| |.....:.:.:...|:.:..|.|:  ....|:::.::|   ||::
  Fly   105 FKVAGPFIRVLQVDCASYQKESLLVEFVKEYCPNLEEISYSNATDEFHYRSIMSKMTH---LKRV 166

  Fly   357 SLENIELDDDICAEIAKNEALEAVNL--------------------------------------- 382
            ::|.::.:|.:..::..|:.||...|                                       
  Fly   167 TIECLDAEDVLNFDMQPNQELEFFELVNGCYTGQNLCGFPNLKTLVLRDCLLWNSMEFGIPLKSL 231

  Fly   383 ----------------------------------------------------TMASGLTSNSVRL 395
                                                                |:.:.:|||.:.:
  Fly   232 HTLDLDDCCFEVMNVSLYQKIAESCTNLVELIFSGCDTNFEVIANLPKLERCTLKTWMTSNELNI 296

  Fly   396 -------------------------------MMESLTSLSSLNISWTDLSADAVTALVTHISPNL 429
                                           .:..|:||:.|..|..|:..|........:| .|
  Fly   297 GFLTVLAEKRGNKLTHLHLSGQFNITNEHARCLGQLSSLTDLRFSNNDILDDDHFKFFNDLS-QL 360

  Fly   430 IRLNIAGCRRVLFDSHVATLQKRCPQLLELDLSDCNSLTPT-VITAI 475
            .|..:..|.||: |..:..:.::||||..:||:||..:|.. ||.||
  Fly   361 ERFGLTACGRVM-DVGMMRMLRKCPQLKVIDLTDCEQITEEFVIQAI 406

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Skp2NP_730815.2 F-box-like 239..284 CDD:289689 12/47 (26%)
leucine-rich repeat 302..327 CDD:275381 4/25 (16%)
AMN1 309..480 CDD:187754 47/293 (16%)
leucine-rich repeat 328..352 CDD:275381 5/25 (20%)
leucine-rich repeat 353..376 CDD:275381 5/22 (23%)
leucine-rich repeat 377..402 CDD:275381 8/146 (5%)
leucine-rich repeat 403..428 CDD:275381 6/24 (25%)
leucine-rich repeat 429..455 CDD:275381 7/25 (28%)
leucine-rich repeat 456..480 CDD:275381 10/21 (48%)
leucine-rich repeat 481..500 CDD:275381
leucine-rich repeat 506..529 CDD:275381
CG9316NP_610051.2 leucine-rich repeat 208..221 CDD:275381 0/12 (0%)
leucine-rich repeat 231..258 CDD:275381 0/26 (0%)
leucine-rich repeat 259..279 CDD:275381 0/19 (0%)
leucine-rich repeat 280..309 CDD:275381 4/28 (14%)
AMN1 310..>411 CDD:187754 27/99 (27%)
leucine-rich repeat 310..334 CDD:275381 1/23 (4%)
leucine-rich repeat 335..359 CDD:275381 6/24 (25%)
leucine-rich repeat 360..385 CDD:275381 7/25 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45457957
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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