Protein Alignment Skp2 and Fbxl13

DIOPT Version :9

• Sequence 1: NP_730815.2
• Gene: Skp2 / 40548
• FlyBaseID: FBgn0037236
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: XP_011248071.1
• Gene: Fbxl13 / 320118
• MGIID: 2443416
• Length: 889
• Species: Mus musculus
• Alignment Length: 394
• Identity: 84/394 - (21%)
• Similarity: 156/394 - (39%)
• Gaps: 118/394 - (29%)

  Fly   242 LSDEILLDIFKWLPKKTLLRMATVCRRFNRCSRDETLWTRLDLG-LRTIRPGALEQIVRRGVL-V 304
            |.::.:|.||.:|..|.::..:.|.|.:....:..:||..:|.. ::.|....:...:::..| |
Mouse   243 LPEQAILQIFLYLTFKDMMACSRVNRSWMAMIQRGSLWNSIDFSTVKNIADKCVVTTLQKWRLNV 307

  Fly   305 IRLAQTSIQEPAFAPYTEVFRTR----------LQ--------------------------YLDL 333
            :||......          |||:          ||                          ||:|
Mouse   308 LRLNFRGCD----------FRTKTLKAVSHCKNLQELNVSDCQSFTDESMRHISEGCPGVLYLNL 362

  Fly   334 SMASITRSSLLTL-----------LSHCRQ-----LKKISLEN-----IELDDDICAEIA----K 373
            |..:||..::..|           |::||:     |:.::|.|     |.||...|.:|:    :
Mouse   363 SNTTITNRTMRLLPRYFHNLQNLSLAYCRKFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFR 427

  Fly   374 NEALEA---VNLTM--ASGLTSNSVRLMMESLTSLSS-LNISWTDLSADAVTALVTHISPNLIRL 432
            |.|...   |:||:  ...||.|.|::::|....:|| :.|....:|..|..||   .|.:|.::
Mouse   428 NIASSCTGIVHLTINDMPTLTDNCVKVLVEKCPRISSVVLIGSPHISDSAFKAL---SSCDLKKI 489

  Fly   433 NIAGCRRVLFDSHVATLQKRCPQLLELDLSDCNSLTPTVITAIMKFKMLEYLSVSRCYLI----- 492
            ...|.:|: .|:...::.:..|.:..:.:.||..||.:.:.::...|.|..|:::.|..|
Mouse   490 RFEGNKRI-SDACFKSIDRNYPGINHIYMVDCKGLTDSSLKSLSLLKQLTVLNLTNCIRIGDIGL 553

  Fly   493 ------PATKFIELKSM--------------------PSLTYLDIFGM--LSDTAMEVLEKQLPK 529
                  ||:  |.|:.:                    |:|.||::...  |:|.|:|.:...|..
Mouse   554 KHFFDGPAS--IRLRELNLTNCSLLGDSSVIRLSERCPNLHYLNLRNCEHLTDLAIEYIASMLSL 616

  Fly   530 MGIN 533
            :.::
Mouse   617 ISVD 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Skp2	NP_730815.2	F-box-like	239..284	CDD:289689	10/41 (24%)
		leucine-rich repeat	302..327	CDD:275381	6/25 (24%)
		AMN1	309..480	CDD:187754	50/237 (21%)
		leucine-rich repeat	328..352	CDD:275381	11/60 (18%)
		leucine-rich repeat	353..376	CDD:275381	9/31 (29%)
		leucine-rich repeat	377..402	CDD:275381	8/29 (28%)
		leucine-rich repeat	403..428	CDD:275381	8/25 (32%)
		leucine-rich repeat	429..455	CDD:275381	4/25 (16%)
		leucine-rich repeat	456..480	CDD:275381	4/23 (17%)
		leucine-rich repeat	481..500	CDD:275381	7/29 (24%)
		leucine-rich repeat	506..529	CDD:275381	8/24 (33%)
Fbxl13	XP_011248071.1	F-box-like	240..284	CDD:372399	10/40 (25%)
		leucine-rich repeat	255..268	CDD:275381	3/12 (25%)
		leucine-rich repeat	280..306	CDD:275381	3/25 (12%)
		AMN1	306..475	CDD:187754	39/178 (22%)
		leucine-rich repeat	307..330	CDD:275381	6/32 (19%)
		leucine-rich repeat	331..356	CDD:275381	2/24 (8%)
		leucine-rich repeat	357..381	CDD:275381	7/23 (30%)
		leucine-rich repeat	382..409	CDD:275381	6/26 (23%)
		leucine-rich repeat	410..435	CDD:275381	7/24 (29%)
		leucine-rich repeat	436..461	CDD:275381	8/24 (33%)
		leucine-rich repeat	462..484	CDD:275381	7/24 (29%)
		AMN1	473..605	CDD:187754	28/137 (20%)
		leucine-rich repeat	486..511	CDD:275381	4/25 (16%)
		leucine-rich repeat	512..536	CDD:275381	4/23 (17%)
		leucine-rich repeat	537..564	CDD:275381	6/28 (21%)
		leucine-rich repeat	565..590	CDD:275381	1/24 (4%)
		leucine-rich repeat	591..610	CDD:275381	7/18 (39%)
		leucine-rich repeat	617..645	CDD:275381	0/4 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843165
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840