Protein Alignment Skp2 and Fbxl17

DIOPT Version :10

• Sequence 1: NP_730815.2
• Gene: Skp2 / 40548
• FlyBaseID: FBgn0037236
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: XP_038939705.1
• Gene: Fbxl17 / 316663
• RGDID: 1309773
• Length: 739
• Species: Rattus norvegicus
• Alignment Length: 308
• Identity: 66/308 - (21%)
• Similarity: 124/308 - (40%)
• Gaps: 62/308 - (20%)

  Fly   241 RLSDEILLDIFKWLP-KKTLLRMATVCRRFNRCSRDETLWTRLDLGLR-TIRPGALEQIVRRGVL 303
            :|...|||.||..|. .:..|..:.||:.:.....|...|.:|||..| .:....||:|..|...
  Rat   318 QLPPSILLKIFSNLSLDERCLSASLVCKYWRDLCLDFQFWKQLDLSSRQQVTDELLEKIASRSQN 382

  Fly   304 VIRLAQTSIQE-------------PAFAPYTEVFRTRLQYLDLSMASITRSSLLTLLSHCRQLKK 355
            ::.:..:..:.             |....|| .:|.:         .::.:|::.:.|||..|:|
  Rat   383 IVEINISDCRSMSDSGVCVLAFKCPGLLRYT-AYRCK---------QLSDTSIIAVASHCPLLQK 437

  Fly   356 ISLENIE-LDDDICAEI-AKNEALEAVNLTMASGLTSNSVRLMMESLTSLSSLNISWTDLSAD-A 417
            :.:.|.: |.|:...:: :|...|:.::......::...:.::.:|...|..:.:....|..| :
  Rat   438 VHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMVVIAKSCLKLQRIYMQENKLVTDQS 502

  Fly   418 VTALVTHISPNLIRLNIAGC----RRVLFDSHVATLQKRCPQLLELDLSDCNSLTPTVITAIMKF 478
            |.|...| .|:|..:...||    :.|:   |:..|:    .|..|||.....|....:..|:|
  Rat   503 VKAFAEH-CPDLQCVGFMGCSVTSKGVI---HLTKLR----NLSSLDLRHITELDNETVMEIVK- 558

  Fly   479 KMLEYLSVSRCYLIPATKFIELKSMPSLTYLDIFGMLSDTAMEVLEKQ 526
                     ||           |::.||. |.:..:::|..:||:.|:
  Rat   559 ---------RC-----------KNLSSLN-LCLNWIINDRCVEVIAKE 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Skp2	NP_730815.2	F-box_DmSKP2-like	239..281	CDD:438920	12/40 (30%)
		leucine-rich repeat	302..327	CDD:275381	4/37 (11%)
		AMN1	309..480	CDD:187754	36/190 (19%)
		leucine-rich repeat	328..352	CDD:275381	4/23 (17%)
		leucine-rich repeat	353..376	CDD:275381	6/24 (25%)
		leucine-rich repeat	377..402	CDD:275381	2/24 (8%)
		leucine-rich repeat	403..428	CDD:275381	6/25 (24%)
		leucine-rich repeat	429..455	CDD:275381	6/29 (21%)
		leucine-rich repeat	456..480	CDD:275381	7/23 (30%)
		leucine-rich repeat	481..500	CDD:275381	2/18 (11%)
		leucine-rich repeat	506..529	CDD:275381	6/21 (29%)
Fbxl17	XP_038939705.1	F-box_FBXO13	315..363	CDD:438864	14/44 (32%)
		leucine-rich repeat	357..382	CDD:275381	9/24 (38%)
		leucine-rich repeat	383..408	CDD:275381	0/24 (0%)
		AMN1	406..568	CDD:187754	41/201 (20%)
		leucine-rich repeat	409..434	CDD:275381	7/34 (21%)
		leucine-rich repeat	435..460	CDD:275381	6/24 (25%)
		leucine-rich repeat	461..486	CDD:275381	2/24 (8%)
		leucine-rich repeat	487..512	CDD:275381	6/25 (24%)
		leucine-rich repeat	513..536	CDD:275381	6/29 (21%)
		leucine-rich repeat	537..562	CDD:275381	9/45 (20%)
		leucine-rich repeat	563..588	CDD:275381	7/24 (29%)