DRSC/TRiP Functional Genomics Resources

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Protein Alignment Skp2 and gadr-3

DIOPT Version :9

Sequence 1:NP_730815.2 Gene:Skp2 / 40548 FlyBaseID:FBgn0037236 Length:559 Species:Drosophila melanogaster
Sequence 2:NP_498378.2 Gene:gadr-3 / 185933 WormBaseID:WBGene00018561 Length:710 Species:Caenorhabditis elegans


Alignment Length:225 Identity:55/225 - (24%)
Similarity:93/225 - (41%) Gaps:44/225 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   325 RTRLQYLDLSMASITRSSLLTLLSHCRQLKKISLENI--------ELDDDICAEIAKNEALEAVN 381
            |..|:.:|.....|.|::::.|..||  |:.:.:.::        :|.||...:|.  |.|:|: 
 Worm    59 RLELRNVDYGKFKIDRNTVMVLKKHC--LESLGIGDLDYIGYYYRDLIDDNTIDIF--ELLKAI- 118

  Fly   382 LTMASGLTSNSVRLMMESLTSLSSLNISWTDLSADAVTALVTHISPNLIRLNIAGCRRVLFDSHV 446
                         |..|:..:|..|:|..:...:...|..:..|.|.|..|.|  |.|.|.....
 Worm   119 -------------LNNETRRNLHYLDIKGSHAFSKKWTKNIGTILPVLRSLII--CGRHLQSDDF 168

  Fly   447 ATLQKRCPQLLELDLSDCNSLTPTVITAIMKFKMLEYLSVSRCYLIPATKFIELKSMPSLTYLDI 511
            ..|.:..|.|..||:|:.|  .|. |:.|...|.||.|.:....|....:|::|.::..|..||:
 Worm   169 QQLCESIPNLTYLDISETN--VPN-ISGISSLKNLESLIMRSVELECFEQFVDLFNLTGLRILDV 230

  Fly   512 FGML--SDTAMEVLEKQLPKMGINKFIHSS 539
            ...:  .||.:           ||:::.|:
 Worm   231 SRSMYKHDTKI-----------INQYVQSN 249

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Skp2NP_730815.2 F-box-like 239..284 CDD:289689
leucine-rich repeat 302..327 CDD:275381 1/1 (100%)
AMN1 309..480 CDD:187754 40/162 (25%)
leucine-rich repeat 328..352 CDD:275381 7/23 (30%)
leucine-rich repeat 353..376 CDD:275381 5/30 (17%)
leucine-rich repeat 377..402 CDD:275381 4/24 (17%)
leucine-rich repeat 403..428 CDD:275381 5/24 (21%)
leucine-rich repeat 429..455 CDD:275381 7/25 (28%)
leucine-rich repeat 456..480 CDD:275381 8/23 (35%)
leucine-rich repeat 481..500 CDD:275381 5/18 (28%)
leucine-rich repeat 506..529 CDD:275381 5/24 (21%)
gadr-3NP_498378.2 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C160162740
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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