Protein Alignment Skp2 and Fbxl7

DIOPT Version :10

• Sequence 1: NP_730815.2
• Gene: Skp2 / 40548
• FlyBaseID: FBgn0037236
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: XP_061500383.1
• Gene: Fbxl7 / 1267513
• VectorBaseID: AGAMI1_014086
• Length: 841
• Species: Anopheles gambiae
• Alignment Length: 547
• Identity: 126/547 - (23%)
• Similarity: 196/547 - (35%)
• Gaps: 163/547 - (29%)

  Fly    22 RSTNKNHVSVVGAL------VSTTKSSHYEHPSSPSALTFEALEEMGIGMLDSEESSSSALSAIA 80
            :|....|:..||:.      :..|||.||.          :.|...|       ..|.:......
Mosquito   334 QSPRGTHLKAVGSADFIDGRIPLTKSQHYT----------DGLSRYG-------RFSPNLDQGYH 381

  Fly    81 LAVSATSDDNSNETTPCASVSRMAHQLQHTQRLSLGSTGDITLDSPAVEDSLSMSRQSAEKLQIL 145
            ..||.:.......|.|.:..:...|          ||.|..|       :|.|.|..|.
Mosquito   382 TLVSPSPSGQQQSTIPASWTTGGTH----------GSGGGGT-------NSTSSSHGSP------ 423

  Fly   146 AQAKRSSLGSEGSGNSNSPSKRLRNPLAAVTCNNQIDGTASLNFQPSTSRLAQVRQAKKPSTTNI 210
            ||. .:.:|..||.|.|.|            |...|||                        ..|
Mosquito   424 AQT-NTPVGGNGSANGNGP------------CGRSIDG------------------------ATI 451

  Fly   211 TTRIVAADSFFVFRTPAMSAHINSGINYFERLSDEILLDIFKWLPKKTLLRMATVCRRFNRCSRD 275
            .|.:.......::|...:          |:|:.||:::.||:||....|..:|.|||||.....:
Mosquito   452 LTSLGNGHGTSLYRAGPL----------FDRMPDELMVRIFEWLDSSELCNIARVCRRFESVIWN 506

  Fly   276 ETLWTRL---------DLGLRTI--------RPGALEQIVRRGVLV---IRLAQTSIQE-----P 315
            ..||..:         |..::||        |.||...:.|  ||:   .||....:|.     |
Mosquito   507 PALWKIIKIKGEENSGDRAIKTILRRLCGQTRNGACPGVER--VLLADGCRLTDRGLQLLSRRCP 569

  Fly   316 AFAPYTEVFRTRLQYLDLSMASITRSSLLTLLSHCRQLKKISLENIELDDDICAEIAKNEALEAV 380
                  |:...::|    :..:||..:|..|::.|..|:       .||...||:|.      .:
Mosquito   570 ------EITHLQIQ----NSVTITNQALSDLVTKCTNLQ-------HLDITGCAQIT------CI 611

  Fly   381 NLTMASGLTSNSVRLMME--SLTSLSSLNISWTDLSADAVTALVTHISPNLIRLNIAGCRRVLFD 443
            |:.  .||.... ||:::  .||..:|:        .||...::....|.|:.|.:..|.:|. |
Mosquito   612 NIN--PGLEPPR-RLLLQYLDLTDCASI--------CDAGIKVIARNCPLLVYLYLRRCIQVT-D 664

  Fly   444 SHVATLQKRCPQLLELDLSDCNSLTPTVITAIMKF-KMLEYLSVSRCYLI--PATKFIELKSMPS 505
            :.:..:...|..|.||.:|||.|:|...:..:.|. ..|.||||::|..:  ...|.|..:.. .
Mosquito   665 AGLKFIPNFCIALRELSVSDCTSVTDFGLYELAKLGATLRYLSVAKCDQVSDAGLKVIARRCY-K 728

  Fly   506 LTYLDIFG--MLSDTAMEVLEKQLPKM 530
            |.||:..|  .:||.::.||.:..|::
Mosquito   729 LRYLNARGCEAVSDDSINVLARSCPRL 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Skp2	NP_730815.2	F-box_DmSKP2-like	239..281	CDD:438920	17/41 (41%)
		leucine-rich repeat	302..327	CDD:275381	7/32 (22%)
		AMN1	309..480	CDD:187754	41/178 (23%)
		leucine-rich repeat	328..352	CDD:275381	6/23 (26%)
		leucine-rich repeat	353..376	CDD:275381	6/22 (27%)
		leucine-rich repeat	377..402	CDD:275381	6/26 (23%)
		leucine-rich repeat	403..428	CDD:275381	3/24 (13%)
		leucine-rich repeat	429..455	CDD:275381	6/25 (24%)
		leucine-rich repeat	456..480	CDD:275381	9/24 (38%)
		leucine-rich repeat	481..500	CDD:275381	8/20 (40%)
		leucine-rich repeat	506..529	CDD:275381	8/24 (33%)
Fbxl7	XP_061500383.1	None