DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9776 and D1044.6

DIOPT Version :9

Sequence 1:	NP_649455.1	Gene:	CG9776 / 40546	FlyBaseID:	FBgn0027866	Length:	1260	Species:	Drosophila melanogaster
Sequence 2:	NP_498184.3	Gene:	D1044.6 / 175762	WormBaseID:	WBGene00017031	Length:	1006	Species:	Caenorhabditis elegans

Alignment Length:	875	Identity:	160/875 - (18%)
Similarity:	288/875 - (32%)	Gaps:	264/875 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   517 DHDPFP--TFENAPARRVPVR-------------------GMQFLVPANAWFCKLC--------- 551
            |.:|||  |.|..|.:.:..|                   ..:.:|..:.:..:||
Worm    19 DKEPFPAMTHELPPEKSLKARLLEQEDERISNVLAHEKRFSTEPVVIDDVFMSRLCVDSQPGCSR 83

  Fly   552 -------SVWIGDLHCASAHLKSRLHSNKYQQFLNQNPNYE--------IEWQTN-------RER 594
                   :|:..||.  |..|.|.....:.::.:.|...:|        |.|...       :.|
Worm    84 IPDIDIANVFRDDLE--SCTLSSSEDEEEEEEPIGQISTFEMLHAPRKPIVWSEQELSDFDMKSR 146

  Fly   595 AMNQQKDHDD-----------AK----NKKSKKDEDKASKKRKKKG-----------GDKKKKKR 633
            .::.:.||.|           ||    |.:..:...:..|:|..||           .....|..
Worm   147 LLDMRMDHWDLARIANVPKRIAKGETVNLRMPRYSAEVVKQRIAKGVTDIFGHFSLVPHTLTKSH 211

  Fly   634 KHGKKSKRSTIDA-NSTSSSSDSSSSEEENGQQPKKGRTEQQPICQSDKSTNAASIRVAMRKQES 697
            |...:.|:..|:. :...:..|.::         :.|..|.:......|..|..:..::..|
Worm   212 KPVAERKQILIERYHDLMNDFDYAT---------RPGSVESKKYANLTKRLNLCNDFLSAPK--- 264

  Fly   698 TPTNLKPEVPCQPVVPPPPPIIKDSTIPSERGKWTAASVEDQSKDQKNRDDTMLKQWNNVQPVIS 762
            .|..|.|.:..:.:.||..|  |:   |.:|           ...:...||:::     :.|...
Worm   265 LPHRLFPRLIIRSIRPPETP--KE---PVKR-----------KMRESESDDSVI-----IIPRKI 308

  Fly   763 ESEK----------KLLEQLKGRLKNKGARDQNNHKAVPTEANDEKFRRGGGRHSRSRSKRRSYS 817
            |.||          |.:|..|.|.::.        :.||.:...||.|...   ..|.::.|.::
Worm   309 EKEKPRPTTENVVLKKVEMEKKRPRSP--------ELVPKKIVMEKERPSS---PDSEAEEREHN 362

  Fly   818 RSISRGRDRDRRDRERD-RDRGRRRRSRSRGRHFSRSPIRSSRRSRSRQGRSRRSRSRSIERVER 881
            ..|    :::|..:|.: |....|:|.:.|..|..|:.....|:..:....|.|.::....::|.
Worm   363 LRI----EKERHQKELEFRREALRKREQEREEHKKRAQEELRRQMTAALEESTRRQAEMNRQIED 423

  Fly   882 PVVKHSEFRPRTVPERKQTDI---------KRDKKDAESKSKSSKPSNNSLPGGKKLPFIGKMPV 937
            ...|..|.: |...|:|:..:         :::|:||| :.:..:.:...|.|.|.:
Worm   424 EARKRDELQ-RIAEEKKRKQLLEDQCRAKQEKEKRDAE-ELEQMRLNIARLAGTKDV-------- 478

  Fly   938 FKKQSVPSFNYDASAVYTNGCLEAPPPPPPPLGGATSQIAVRQQAPTAAQIQMAMMEDAFGNAPP 1002
                        .:|:.:...:|..||............||:.:.|.    .....:|.|.....
Worm   479 ------------ENALKSPSLVEIVPPSDARAFEMIKWNAVKCKIPE----NWEKRKDKFYRVFE 527

  Fly  1003 FHPDAGMM-VDYDELMPDPVQFANLMTSCPPPPP---PGEGSEGDAHGPEDGDQHDNENREDV-L 1062
            :..||... ::.||::           |.|...|   |.|            |.:...||..: |
Worm   528 WPSDAAQRDIERDEVV-----------SIPRSKPIVIPQE------------DTYITRNRIPLKL 569

  Fly  1063 PPGIDEAESALV-------PHPLDAAAQSRDG-ELPKDLVEALDIIFPSDVAILEASNGNSEKQE 1119
            ||.:.:|..|||       ...:.||..:.:| :.|   .|.::|    |..:.|.....:..:.
Worm   570 PPKVKQAVPALVVRNSNNATRTVVAATVNENGIQWP---AETINI----DEVVREIRGLMAPTRR 627

  Fly  1120 DVTITTIVEDDAV-LSVIHLQDLAKEGI------------HLVTINEAEVPKKSHIQTSEKIEKL 1171
            :..|:...:.|.: ...|:|..| |.||            .||.:..::..|....:..|.:...
Worm   628 NFAISLSPKTDEIDYQAINLNRL-KSGIVYPFYFSDGLYWPLVFLKSSKNGKPEAQRHVEALTSC 691

  Fly  1172 QDLNG-----------KSDDGVNIKLIDA-------------EDIPMPNSPPAEPSFDEETKSKA 1212
            :..:|           |.:|....|..||             :.....|....:|.:|....|..
Worm   692 KSFSGKYASRYLLTTTKEEDSATKKFEDAYADSDGDWADYSTKPGRFSNRAGFKPHYDTSNDSFE 756

  Fly  1213 LQKQADISEIPEPAVSPSDSEKLRRQSELD 1242
            :|||.        ||...:|:..:.::|||
Worm   757 VQKQR--------AVDSLNSQYEKERNELD 778

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9776	NP_649455.1	bZIP	<289..322	CDD:304365
CG9776	NP_649455.1	ZnF_U1	546..577	CDD:197732	8/46 (17%)
D1044.6	NP_498184.3	ARGLU	322..461	CDD:291991	33/155 (21%)
D1044.6	NP_498184.3	Selenoprotein_S	<371..>464	CDD:284376	20/94 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159658
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15577
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030