Protein Alignment Syt14 and SYT8

DIOPT Version :9

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_011518757.1
• Gene: SYT8 / 90019
• HGNCID: 19264
• Length: 539
• Species: Homo sapiens
• Alignment Length: 374
• Identity: 89/374 - (23%)
• Similarity: 148/374 - (39%)
• Gaps: 86/374 - (22%)

  Fly   196 CGEHRAKTQALRYQHRVNVAAPPKLDKERDNVLVVPMVNAYSINNNNNSITTSNNHPSSNNNDDE 260
            |..||.|.:                |||           :..:.:...:.||....|
Human   212 CRRHRKKPR----------------DKE-----------SVGLGSARGTTTTHLVQP-------- 241

  Fly   261 PLFDTSDLRSIKSDDLLVGVDQKEPAVQRGPIELELSLLYDAPMRKMTVHVMQAKNLPPLGSGQT 325
               |...|.|...|           |.|.|.  |:|||.:|...:::.|.:.||.:|.|   |.|
Human   242 ---DVDGLESSPGD-----------AQQWGC--LQLSLEFDFGSQEIRVGLRQAADLRP---GGT 287

  Fly   326 THTQVRMLMLPSKKQKLKTKIRSGE-NPQYMESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLI 389
            .....|:.:......:.:||:..|. .|.:.|:...| :...::....|:|:|:..:|......:
Human   288 VDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFH-IPQAELPGATLQVQLFNFKRFSGHEPL 351

  Fly   390 GEAYVSFATVDLELETNLWLPLEPRNTSSGLGSTSDLLSLARSESAGSTSSMQHGGVSELLLGLS 454
            ||..:...||||:.....|..|                        |..::.|...|.||...|.
Human   352 GELRLPLGTVDLQHVLEHWYLL------------------------GPPAATQPEQVGELCFSLR 392

  Fly   455 YNGVTGRLSVEIIKGSQFRSLSLNKAPDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAF 519
            |...:|||:|.:::.   |.|....| :.|||:.::.: .::..:.||:.::|...|.|.|.|.|
Human   393 YVPSSGRLTVVVLEA---RGLRPGLA-EPYVKVQLMLN-QRKWKKRKTATKKGTAAPYFNEAFTF 452

  Fly   520 QVALFQLNDVTLMISVYAKRHMKKNEMVGWFSLGLNSSGSEEVAHWADV 568
            .|...|:.:|.|:::|:.:....:.|.||...||..:|| :.:.||||:
Human   453 LVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASG-QPLQHWADM 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	31/122 (25%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	39/123 (32%)
SYT8	XP_011518757.1	C2	257..370	CDD:301316	30/118 (25%)
		C2	385..514	CDD:301316	38/122 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810