DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Syt14 and Pla2g4d

DIOPT Version :9

Sequence 1:	NP_001262249.1	Gene:	Syt14 / 40544	FlyBaseID:	FBgn0261086	Length:	648	Species:	Drosophila melanogaster
Sequence 2:	XP_001080051.2	Gene:	Pla2g4d / 691905	RGDID:	1593372	Length:	825	Species:	Rattus norvegicus

Alignment Length:	175	Identity:	43/175 - (24%)
Similarity:	76/175 - (43%)	Gaps:	37/175 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   461 RLSVEIIKGSQFRSLSLNKAPDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAFQVALFQ 525
            :|:|:|::........|....|.||.:.:.::.|::.   ||.......||::.|||:|.:. .|
  Rat    32 QLTVKILEARSLPRADLLSKADPYVTLRLPTASGRKF---KTQTVTNSSNPVWNETFSFLIQ-SQ 92

  Fly   526 LNDVTLMISVYAKRHMKKNEMVGWFS---------------LGLNSSGSEEVAHWADV------- 568
            :.:: |.::||.:..:.|:::....|               ..||..|.||:    ||
  Rat    93 VKNI-LELTVYDEDLITKDDICFKISYDISEILPGQLVQKTFSLNPQGPEEL----DVEFLVERT 152

  Fly   569 CEMPKGEMLARWHVLVDSXFEQLGQSSGRSGKALRKLSLAAFKDR 613
            |:.|  |.|...:|||.. ...|..|..|:|..    ::||.:|:
  Rat   153 CDPP--ENLITNNVLVARELSHLDVSLDRAGST----TMAAGQDK 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035
Syt14	NP_001262249.1	C2B_Synaptotagmin-14_16	446..584	CDD:176053	34/144 (24%)
Pla2g4d	XP_001080051.2	C2_cPLA2	32..151	CDD:176001	29/127 (23%)
		PLAc	267..758	CDD:214474
		Patatin_and_cPLA2	278..814	CDD:299702
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900