Protein Alignment Syt14 and sytl2b

DIOPT Version :9

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_701277.6
• Gene: sytl2b / 572466
• ZFINID: ZDB-GENE-121214-363
• Length: 1737
• Species: Danio rerio
• Alignment Length: 587
• Identity: 126/587 - (21%)
• Similarity: 217/587 - (36%)
• Gaps: 141/587 - (24%)

  Fly    72 KRRYENTSSDSEEDILRRLRWHQQHQLGEKPGGYGLGIS-------------QANPLTAQSF--- 120
            :||...||.||:...|.|....:.:|       :.||||             |.:.....||
Zfish  1185 QRRTSRTSEDSDSQPLARSYIPRDYQ-------HYLGISEDKSMYTPPPVAEQVDDFICTSFTSS 1242

  Fly   121 ---NYH----------QAGASADLQ--------RVTVSRDPLAIAERGKV--GIPSSHSE----- 157
               |:.          ....|.|||        .:|...|       |.:  ||.:..:|
Zfish  1243 PETNHSCKCPPVKTSTPVHGSPDLQTRSGSLGHHLTTQTD-------GNIIKGIQNRENESLIQK 1300

  Fly   158 ----CSSNDSMEVSVDSHTGVLTGLSK-------------ATTTVPHPATAFRNPCGEHRAKTQA 205
                .||......|::..:.:.....|             |::|  |..|:|.....||..|
Zfish  1301 ALKRASSRPVYHKSMEDISSIARQDQKLKQTDDYMHDNYDASST--HLQTSFSTADPEHMKK--- 1360

  Fly   206 LRYQHRVNVAAPPKLDKERDNVLVVPMVNAYSINNNNNSITTSNNHPSSNNNDDEPLFDTSDLRS 270
                  ::.:.|..|:||.|.      ..:.|.:::..|:...||...:|.::   ...::.|.|
Zfish  1361 ------LSKSVPSFLEKESDG------GESDSESSSRGSVPKWNNRQFTNLSN---YSGSTSLSS 1410

  Fly   271 IKSDDLLVGVDQKEPAVQRGPIELELSLLYDAPMRKMTVHVMQAKNLPPLGSGQT-THTQVRMLM 334
            :......|..........:|.|  :.||.|...:|:..:.|:|.:||..:.:.:. :...|:..:
Zfish  1411 VSGSVASVYTSDYNSVDVQGSI--QFSLNYVHKLREFHIFVVQCQNLAAVDAKRNRSDPYVKSYL 1473

  Fly   335 LPSKKQ--KLKTKIRSGE-NPQYMESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEAYVSF 396
            :|....  |.||.::... ||.|.| .|.:||..|.:.:..|.:..:..:...:...:||..:..
Zfish  1474 IPDPANLGKRKTAVKKKTLNPTYNE-ILRYRVRMEYLTSQVLNLSAWHNDMFGRNSFLGEIELDL 1537

  Fly   397 ATVDLELETNLWLPLEPRN----TSSGLGSTSDLLSLARSESAGSTSSMQHGGVSELLLGLSYN- 456
            :|.|........|||:|||    |::.| ..|||....|.             ....|..:|::
Zfish  1538 STWDFNDTERKLLPLKPRNLFIQTTNSL-QPSDLKGQMRL-------------AIRFLPQISHSK 1588

  Fly   457 GVTGRLSVEI-IKGSQFRSLSLNKAP--DTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFA 518
            .|.|...|.| :|  ..::|.|.::|  |.|||..::....:: ||.||.:.:...||:|..|..
Zfish  1589 NVPGSGEVHIWVK--DCKNLPLIRSPTIDPYVKCFVLPDTSKK-SRQKTRVLKRTTNPIFNHTMV 1650

  Fly   519 FQ-VALFQLNDVTLMISVYAKRHMKKNEMVGWFSLGLNS------------SGSEEVAHWADVCE 570
            :. .....|.:..:.::|:.:..:..:.: |...||:.:            |.:||||.|..:..
Zfish  1651 YDGFRAEDLKEACVELTVWDRDRLASHSL-GGLRLGMGTGRSYGVQVDWMDSTTEEVALWRRMMN 1714

  Fly   571 MP 572
            .|
Zfish  1715 SP 1716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	30/125 (24%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	34/144 (24%)
sytl2b	XP_701277.6	PHD_SF	5..>47	CDD:304600
		C2	1429..1553	CDD:301316	30/126 (24%)
		C2B_SLP_1-2-3-4	1571..1727	CDD:175987	35/163 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810