Protein Alignment Syt14 and sytl2a

DIOPT Version :10

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_009303749.1
• Gene: sytl2a / 563188
• ZFINID: ZDB-GENE-130723-2
• Length: 1447
• Species: Danio rerio
• Alignment Length: 536
• Identity: 111/536 - (20%)
• Similarity: 207/536 - (38%)
• Gaps: 94/536 - (17%)

  Fly    92 WHQQHQLG----EKPGGYGLGISQ------ANPLTAQSFNYHQAGASADLQRVTVSRDPLAIAER 146
            :.|.||.|    ..|..:.|..|:      :...|.::::...|.:..|.:.....:..|..|..
Zfish   950 FEQVHQGGVSNESSPSRHSLLESEEITFDSSGSSTPEAWSISHASSYWDSEDDGPFKAALERANA 1014

  Fly   147 GKVGIPSSHSECSSNDSME-VSVDSHTGVLTGLSKATTTVPHPATAFRNPCGEHRAKTQALRYQH 210
            ..:.|..|..:.:|..|.| ...|....|...:...:...|:..|:|.:|   .:.|..:|
Zfish  1015 RPISISKSLEDLASTPSQERWKTDPRNDVRMSMENVSAVPPNTKTSFSDP---EQVKMMSL---- 1072

  Fly   211 RVNVAAPPKLDKE---RDNVLVVPMVNAYSINNNNNSITTSNNHPSSNNNDDEPLFDT-SDLRSI 271
                :.|..:.:|   |::       :..|:::..|....|.|.||:        |.| |::.|:
Zfish  1073 ----SVPALMQQEMECRNS-------DCASVSSFYNDRQRSCNTPSN--------FSTCSEVASM 1118

  Fly   272 KSDDLLVGVDQKEPAVQRGPIE----LELSLLYDAPMRKMTVHVMQAKNLPPLG-SGQTTHTQVR 331
            .|   :.|......:.:.|.:|    ::.::.|...:.:..:.|:|.|:|.... ....:...|:
Zfish  1119 SS---VTGSVMSIYSSEFGYVEVKGTVQFAIHYVQKLGEFHIFVVQCKDLAVADVKRNRSDPYVK 1180

  Fly   332 MLMLPSKKQ--KLKTKIRSGE-NPQYMESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEAY 393
            ..:||.|.:  |.||.:|... :|.|.| .|..::..|.:....|.:.::..:...:...:||..
Zfish  1181 CYLLPDKAKYGKKKTCVRKKTLDPTYNE-ILRFKIPMEMLKTQKLNISVWHNDTFGRNSFLGEVE 1244

  Fly   394 VSFATVDLE--------LETNLWLPLEPRNTSSGLGSTSDLLSLARSESAGSTSSMQHGGVSELL 450
            |..|..|..        |:..:.:|..|:::..|...::::....|.....:.|....|
Zfish  1245 VDLAEWDFNNTQMNEYLLKGRVQIPTSPKHSFGGEEMSAEIKVALRFLPQTTLSHKNKG------ 1303

  Fly   451 LGLSYNGVTGRLSVEI-IKGSQFRSLSLNKAPDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFK 514
                 ||     .|:| :|..:...:|...|.|.:||..::....:: ||.||.:.:..|||:|.
Zfish  1304 -----NG-----EVQIWVKECKNLPISRGVAIDPFVKCAILPENNRK-SRQKTRVLKRAPNPVFN 1357

  Fly   515 ETFAFQ-VALFQLNDVTLMISVYAKRHMKKNEMVGWFSLGL---NSSGSEEVAHWAD--VCEMPK 573
            .|..:. .....|.|:.:.::|:....: .|..:|...||.   .|.|||  .:|.|  |.|
Zfish  1358 HTMVYDGFGHDDLKDICVELTVWDHDRL-NNHFIGGIRLGPGTGKSYGSE--VNWMDSNVAE--- 1416

  Fly   574 GEMLARWHVLVDSXFE 589
               .|.|..:|.:..|
Zfish  1417 ---AALWERMVQTQNE 1429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	27/137 (20%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	36/144 (25%)
sytl2a	XP_009303749.1	PHD_SF	5..>37	CDD:473978
		C2A_SLP-1_2	1139..1263	CDD:176039	24/124 (19%)
		C2B_SLP_1-2-3-4	1283..1438	CDD:175987	41/173 (24%)