Protein Alignment Syt14 and doc2a

DIOPT Version :10

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_073800319.1
• Gene: doc2a / 558815
• ZFINID: ZDB-GENE-090706-1
• Length: 486
• Species: Danio rerio
• Alignment Length: 545
• Identity: 118/545 - (21%)
• Similarity: 198/545 - (36%)
• Gaps: 129/545 - (23%)

  Fly    92 WHQQHQLGEKPGGYGLGISQANPL--TAQS--------FNYHQAGASADLQRVTVSRDPLAIAER 146
            |....|...|.|  ||.|...|.|  |.|.        |...:...|:..|||:...:..::..|
Zfish     2 WWCVDQSSVKAG--GLWIESQNQLIFTEQGLWVRLRICFPLWERNYSSATQRVSPEYNSSSMTVR 64

  Fly   147 -GKVGIPSSHSECSSNDSMEVSVDSHTGVLTGLSKATTTVPHPATAFRNPCGEHRAKTQALRYQH 210
             ||              .:.:|:..|        .|....|.|....|          |...|..
Zfish    65 KGK--------------KLTISIQEH--------MAIDVCPGPIRPIR----------QISAYFP 97

  Fly   211 RVNVAAPPKLDKERDNVLVVPMVNA-------------YSINNNNNSITTSNNHPSSNNNDDEPL 262
            |::..|.|........:.:.|.:.|             ........:::.:::
Zfish    98 RLSPTAEPVSPNPASPLSLSPGLGASGGASGGLLSPLQAGARGGGGTLSAASS------------ 150

  Fly   263 FDTS-DLRSIKSDDLLVGVDQKEPAVQRGPIELELSLLYDAPMRKMTVHVMQAKNLPPLGSGQTT 326
            .:|| |:.|..|||          :...|.:|.||.  |:.....:...:::||.|.|:......
Zfish   151 IETSVDICSSDSDD----------STALGTLEFELR--YEKATSSLNCTIIRAKGLKPMDFNGLA 203

  Fly   327 HTQVRMLMLPS--KKQKLKTK-IRSGENPQYMESFLLHRVNPEDVNNMGLRVRLYGCERLRKERL 388
            ...|::.:||.  |..||||| :|:..||.:.|:.....:..||::...||:.:...::|.....
Zfish   204 DPYVKLHLLPGACKANKLKTKTVRNSLNPVWNETLTYVGITEEDMHRKTLRLSVCDEDKLTHNEF 268

  Fly   389 IGEAYVSFATVDLELETNLWLPLE-----PRNTSSGLGSTSDLLSLARSESAGSTSSMQHGGVSE 448
            |||:.|:...|..:.....:..||     |..|:.|.........|...|:...||..:.|   .
Zfish   269 IGESRVALRRVKPDQTKRFYTCLEHPPPLPSPTAMGAALRGISCYLREWENEQMTSLEERG---R 330

  Fly   449 LLLGLSY---------NGVTGRLSVEIIKGSQFRSLSLNKAPDTYVKMVMVSSIGQEISRAKTSI 504
            |||.|.:         ....|.|.|.:::.:...::.:|...|.|||:.:...:.:: |:.|||:
Zfish   331 LLLSLQFLPPPAEGEGESRRGGLCVGVLRCAHLAAMDVNGFSDPYVKIYLKPDVKKK-SKHKTSV 394

  Fly   505 RRGQPNPLFKETFAFQVALFQLNDVTLMISVYAKRHMKKNEMVGW-FSLGLNSSGSEEVAHWADV 568
            .:...||.|.|.|.::::|.:|...||.::|             | :.||.::...:...:|...
Zfish   395 IKKTLNPEFNEEFFYEISLSELVHKTLEVTV-------------WDYDLGRSNDFIDSTRYWKYS 446

  Fly   569 CEMPKGEMLARWHVLVDSXFEQLGQ 593
            .|           |||.:...||.|
Zfish   447 SE-----------VLVHNSITQLLQ 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	33/129 (26%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	32/147 (22%)
doc2a	XP_073800319.1	None