Protein Alignment Syt14 and Syt7

DIOPT Version :10

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_030106854.1
• Gene: Syt7 / 54525
• MGIID: 1859545
• Length: 719
• Species: Mus musculus
• Alignment Length: 543
• Identity: 127/543 - (23%)
• Similarity: 210/543 - (38%)
• Gaps: 113/543 - (20%)

  Fly    67 QKITRKRRYENTSSDSEEDILRRLRWHQQHQLGEKPGGYGLGISQANPLTAQSFNYHQAGASA-- 129
            |.:::.::....|..:....|.:|:.|.....|..|..||.|  ||...|:....|..||..:
Mouse   262 QPLSQNQQGRQPSQPTTSQSLGQLQAHAASAPGSNPRAYGRG--QARQGTSAGSKYRAAGGRSRS 324

  Fly   130 -----------------DLQ-----RVTVSRDPLAIAERGK-VGIPSSHSECSSNDSMEVSVDSH 171
                             |::     |:.|....|.::|:.. ..||...:. .:..:.....|..
Mouse   325 NPGSWDHVVGQIRNRGLDMKSFLEGRMVVLSLVLGLSEQDDFANIPDLQNP-GTQQNQNAQGDKR 388

  Fly   172 TGVLTGLSKATTTVPHPATAFRNPCGEHRAKTQALRYQHRVNVAAPPKLDKERDNVLVVPMVNAY 236
               |....||..|.|.|.   :.|..|...:|:                             ...
Mouse   389 ---LPAGGKAVNTAPVPG---QTPHDESDRRTE-----------------------------TRS 418

  Fly   237 SINNNNNSITTSNNHPSSNNNDDEPLFDTSDLRSIKSDDLLVGVDQKEPAVQRGPIELELSLLYD 301
            |:::..||:|:.....|..:.:||                     ..|...:.....::.|:.|:
Mouse   419 SVSDLVNSLTSEMLMLSPGSEEDE---------------------AHEGCSRENLGRIQFSVGYN 462

  Fly   302 APMRKMTVHVMQAKNLPPLGSGQTTHTQVRMLMLPSKKQKLKTKI-RSGENPQYMESFLLHRVNP 365
            .....:||.||:|:.||......|:...|::.:||.||.||:||: |...||.:.|:||......
Mouse   463 FQESTLTVKVMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPY 527

  Fly   366 EDVNNMGLRVRLYGCERLRKERLIGEAYVSFATVDLELETNLWLPLEPRNTSSGLGSTSDLLSLA 430
            |.|....|.:::...:|..:...|||..:....|||......|..|:|  .|.|.||.
Mouse   528 EKVVQRVLYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKP--CSDGSGSR------- 583

  Fly   431 RSESAGSTSSMQHGGVSELLLGLSYNGVTGRLSVEIIKGSQFRSLSLNKAPDTYVKMVMVSSIGQ 495
                            .||||.|.||.....:.|.|||....:::.:....|.|||:.::.. .:
Mouse   584 ----------------GELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYK-DK 631

  Fly   496 EISRAKTSIRRGQPNPLFKETFAFQVALFQLNDVTLMISVYAKRHMKKNEMVGWFSLGLNSSGSE 560
            .:.:.||..::...||:|.|:|||.:...:|.:.|::|:|..|..:.:|:::|...|.. .||..
Mouse   632 RVEKKKTVTKKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSW-KSGPG 695

  Fly   561 EVAHWADVCEMPKGEMLARWHVL 583
            ||.||.|:...|: :.:|:||.|
Mouse   696 EVKHWKDMIARPR-QPVAQWHQL 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	37/122 (30%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	44/138 (32%)
Syt7	XP_030106854.1	C2A_Synaptotagmin-7	451..575	CDD:176032	37/123 (30%)
		C2B_Synaptotagmin-7	583..718	CDD:176050	44/161 (27%)