Protein Alignment Syt14 and Syt6

DIOPT Version :9

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_006501767.1
• Gene: Syt6 / 54524
• MGIID: 1859544
• Length: 529
• Species: Mus musculus
• Alignment Length: 585
• Identity: 128/585 - (21%)
• Similarity: 234/585 - (40%)
• Gaps: 137/585 - (23%)

  Fly     5 SASGLDSTPTLGTIEVTTLLGAFFGVLVLLLLLFLFISRKCCFHYRHAINCCDERHLAVKCVQKI 69
            |.|..||..::..:.|..::..     |.|:.:|||:..|.|:
Mouse    48 SPSAADSGTSVSLLAVVVIVCG-----VALVAVFLFLFWKLCW---------------------- 85

  Fly    70 TRKRRYENTSSDSEEDILRRLRWHQQHQLGEKPGGYGLGISQANPLTAQSFNYHQAGASADLQRV 134
                                :.|.::.  ...|       |.|||.:....:....|..||
Mouse    86 --------------------MPWRKKE--ASSP-------SSANPASETLQSPSSRGNMAD---- 117

  Fly   135 TVSRDPLAIAERGKVGIPSSHSECSSNDSMEVSVDSHTGVLTGLSKATTTVPHPATAFRNPCGEH 199
             ..:||.|:... :..:..||:.......:::||..|....|.|.:.||   .||::.|     |
Mouse   118 -KLKDPSALGFL-EAAVKISHTSPDIPAEVQMSVKEHIMRHTKLQRQTT---EPASSTR-----H 172

  Fly   200 RAKTQALRYQHRVNVAAPPKLDKERDNVLVVPMVNAYSINNNNNSITTSNNHPSSNNNDDEPLFD 264
            .:..:.|..|..|:                       |::..|.....:...|:|.......|:.
Mouse   173 TSFKRHLPRQMHVS-----------------------SVDYGNELPPAAAEQPTSIGRIKPELYK 214

  Fly   265 TSDLRSIKSDDLLVGVDQKEPAVQRGPIELELSLLYDAPMRKMTVHVMQAKNLPPLGSGQTTHTQ 329
            .   :|:..||.     :.|.|...|  ::..||.||.....:.|.:::|.:||......::...
Mouse   215 Q---KSVDGDDA-----KSEAAKSCG--KINFSLRYDYESETLIVRILKAFDLPAKDFCGSSDPY 269

  Fly   330 VRMLMLPSKKQKLKTKI-RSGENPQYMESFLLHRVNP-EDVNNMGLRVRLYGCERLRKERLIGEA 392
            |::.:||.:|.||:|:: |...||.:.|:|  |...| |::.:..|.:.::..:|..:..:|||.
Mouse   270 VKIYLLPDRKCKLQTRVHRKTLNPTFDENF--HFPVPYEELADRKLHLSVFDFDRFSRHDMIGEV 332

  Fly   393 YVS--FATVDLELETNLWLPLEPRNTSSGLGSTSDLLSLARSESAGSTSSMQHGGVSELLLGLSY 455
            .:.  |...||..||::|..::                .|.|||.         .:.|::..|.|
Mouse   333 ILDNLFEASDLSRETSIWKDIQ----------------YATSESV---------DLGEIMFSLCY 372

  Fly   456 NGVTGRLSVEIIKGSQFRSLSLNKAPDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAFQ 520
            ....|||::.:||....:::.:....|.|||:.::.. |:.:.:.||:|::...||::.|...|.
Mouse   373 LPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCD-GRRLKKKKTTIKKNTLNPIYNEAIIFD 436

  Fly   521 VALFQLNDVTLMISVYAKRHMKKNEMVGWFSLGLNSSGSEEVAHWADVCEMPKGEMLARWHVLVD 585
            :....::.|:|:|||.....:..||::|...:|:|:.|... .||.::...|: :.:|.||.||:
Mouse   437 IPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGINAEGLGR-DHWNEMLAYPR-KPIAHWHSLVE 499

  Fly   586  585
            Mouse   500  499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	34/125 (27%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	37/137 (27%)
Syt6	XP_006501767.1	C2A_Synaptotagmin-1-5-6-9-10	231..355	CDD:176031	35/143 (24%)
		C2B_Synaptotagmin-3-5-6-9-10	364..497	CDD:176048	37/135 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810