DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syt14 and Syt5

DIOPT Version :9

Sequence 1:	NP_001262249.1	Gene:	Syt14 / 40544	FlyBaseID:	FBgn0261086	Length:	648	Species:	Drosophila melanogaster
Sequence 2:	NP_062223.1	Gene:	Syt5 / 54309	RGDID:	3806	Length:	386	Species:	Rattus norvegicus

Alignment Length:	293	Identity:	74/293 - (25%)
Similarity:	140/293 - (47%)	Gaps:	33/293 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   294 LELSLLYDAPMRKMTVHVMQAKNLPPLGSGQTTHTQVRMLMLPSKKQKLKTKI-RSGENPQYMES 357
            |:.||.||....::.|.::||:.|..|..|.::...|.:.:||.|:::.:||: |...||.:.|:
  Rat   112 LQYSLDYDFQTGQLLVGILQAEGLAALDLGGSSDPYVSVYLLPDKRRRHETKVHRQTLNPHFGET 176

  Fly   358 FLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEAYVSFATVDLELETNLW--LPLEPRNTSSGL 420
            |.. :|...::....|.:.:|..:|..:...|||..|..::|:|......|  |.:.|:.....|
  Rat   177 FAF-KVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVNLGRPVQAWRELQVAPKEEQEKL 240

  Fly   421 GSTSDLLSLARSESAGSTSSMQHGGVSELLLGLSYNGVTGRLSVEIIKGSQFRSLSLNKAPDTYV 485
            |                          ::...|.|....|:|:|.:::....:.:.:....|.||
  Rat   241 G--------------------------DICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYV 279

  Fly   486 KMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAFQVALFQLNDVTLMISVYAKRHMKKNEMVGWF 550
            |:.::.. |:::.:.||:|::...||.:.|.|:|:|...|:..|.:.::|.....:.|||.:|..
  Rat   280 KVHLLQG-GKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRV 343

  Fly   551 SLGLNSSGSEEVAHWADVCEMPKGEMLARWHVL 583
            ::| .:.|...:.||||:...|: ..:|:||.|
  Rat   344 AVG-TAVGGAGLRHWADMLANPR-RPIAQWHSL 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	34/121 (28%)
Syt14	NP_001262249.1	C2B_Synaptotagmin-14_16	446..584	CDD:176053	37/138 (27%)
Syt5	NP_062223.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		Syt1_2_N	6..76	CDD:425364
		C2A_Synaptotagmin-1-5-6-9-10	108..230	CDD:176031	33/118 (28%)
		C2B_Synaptotagmin-1	240..374	CDD:176047	38/162 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810