Protein Alignment Syt14 and Syt3

DIOPT Version :9

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_061995.1
• Gene: Syt3 / 25731
• RGDID: 3805
• Length: 588
• Species: Rattus norvegicus
• Alignment Length: 524
• Identity: 126/524 - (24%)
• Similarity: 195/524 - (37%)
• Gaps: 112/524 - (21%)

  Fly   101 KPGGYGLGISQANPLTAQSFNYHQAG-ASADLQRVTVSRDPLAIAERGKVG-----IPSSHSECS 159
            :|||.| |.....|......:|.:|. ||.....|..|:....:...|..|     :|.|.....
  Rat   148 EPGGLG-GSEPPEPSYLDMDSYPEAAVASVVAAGVKPSQTSPELPSEGGTGSGLLLLPPSGGGLP 211

  Fly   160 SNDSMEVSVDSHTGVLTGLSKAT--TTVPHPATAFRNPCGEHRAKTQALRYQHRVNVAAPPKLDK 222
                   |..||..| |.|:..|  ..:|.|.|                  |..:...|.|. .:
  Rat   212 -------SAQSHQQV-TSLAPTTRYPALPRPLT------------------QQTLTTQADPS-SE 249

  Fly   223 ERDNVLVVPMVNAYSINNNNNSITTSNNHPSSNNNDDEPLFDTSDLRSIKSD--------DLLVG 279
            ||...|.:|:                   |.....       ...:..||.:        ....|
  Rat   250 ERPPALPLPL-------------------PGGEEK-------AKLIGQIKPELYQGTGPGGRRTG 288

  Fly   280 VDQKEPAVQRGPIELELSLLYDAPMRKMTVHVMQAKNLPPLGSGQTTHTQVRMLMLPSKKQKLKT 344
            ....|.....|.|...|..||.:.  ::.|.::||.:||...|...:...|::.:||.:|:|.:|
  Rat   289 GGSGEAGAPCGRISFALRYLYGSD--QLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQT 351

  Fly   345 KI-RSGENPQYMESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEAYVSFATVDLEL----- 403
            |: |...||.:.|:|.. .|...::....|...:|..:|..:..|||:..:...   |||
  Rat   352 KVHRKTLNPIFNETFQF-SVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNL---LELAEQPP 412

  Fly   404 ETNLWLPLEPRNTSSGLGSTSDLLSLARSESAGSTSSMQHGGVSELLLGLSYNGVTGRLSVEIIK 468
            :..||     |:...|....:||                    .||...|.|....|.|:|.|||
  Rat   413 DRPLW-----RDILEGGSEKADL--------------------GELNFSLCYLPTAGLLTVTIIK 452

  Fly   469 GSQFRSLSLNKAPDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAFQVALFQLNDVTLMI 533
            .|..:::.|....|.|||..::|. |:.:.:.||||::...||.:.|...|.||...:.:|.|.|
  Rat   453 ASNLKAMDLTGFSDPYVKASLISE-GRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSI 516

  Fly   534 SVYAKRHMKKNEMVGWFSLGLNSSGSEEVAHWADVCEMPKGEMLARWHVLVDSXFEQLGQSSGRS 598
            :|.....:..||::|...:|..::......|||::...|: :.:..||.||:   |:...|..:.
  Rat   517 AVVDYDCIGHNEVIGVCRVGPEAADPHGREHWAEMLANPR-KPVEHWHQLVE---EKTLSSFTKG 577

  Fly   599 GKAL 602
            ||.|
  Rat   578 GKGL 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	34/127 (27%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	42/137 (31%)
Syt3	NP_061995.1	Cysteine motif. /evidence=ECO:0000250|UniProtKB:O35681	10..34
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	129..161		5/13 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	183..222		10/46 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	238..257		5/19 (26%)
		C2A_Synaptotagmin-1-5-6-9-10	297..422	CDD:176031	36/135 (27%)
		C2B_Synaptotagmin-3-5-6-9-10	431..565	CDD:176048	42/135 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810