DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syt14 and Pla2g4b

DIOPT Version :9

Sequence 1:	NP_001262249.1	Gene:	Syt14 / 40544	FlyBaseID:	FBgn0261086	Length:	648	Species:	Drosophila melanogaster
Sequence 2:	NP_663353.3	Gene:	Pla2g4b / 211429	MGIID:	2384819	Length:	791	Species:	Mus musculus

Alignment Length:	125	Identity:	27/125 - (21%)
Similarity:	45/125 - (36%)	Gaps:	37/125 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   462 LSVEIIKGSQFRSLSLNKAPDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAFQV----- 521
            |:|.:::.|...|..|..:.|.||.:.:.::....:   :|...:...||::.:.|.|::
Mouse    20 LTVRVLRASGLPSKDLVTSSDCYVTLNLPTASSHTL---QTRTVKNSRNPVWNQNFHFRIHRQLK 81

  Fly   522 ------------------ALFQLNDV-TLMISVYAKRHMKKNEMVGWFSLGLNSSGSEEV 562
                              .|..|.|| ||.|....:.          ||||....|..||
Mouse    82 NVMELKVFDHDLVTRDDPVLSVLFDVGTLQIGTQRQS----------FSLGTQEKGCLEV 131

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035
Syt14	NP_001262249.1	C2B_Synaptotagmin-14_16	446..584	CDD:176053	27/125 (22%)
Pla2g4b	NP_663353.3	C2_cPLA2	19..137	CDD:176001	27/125 (22%)
Pla2g4b	NP_663353.3	Patatin_and_cPLA2	250..779	CDD:299702
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900