Protein Alignment Syt14 and Syt3

DIOPT Version :9

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_001107588.1
• Gene: Syt3 / 20981
• MGIID: 99665
• Length: 587
• Species: Mus musculus
• Alignment Length: 533
• Identity: 128/533 - (24%)
• Similarity: 198/533 - (37%)
• Gaps: 131/533 - (24%)

  Fly   101 KPGGYGLGISQANPLTAQSFNYHQAG-ASADLQRVTVSRDPLAIAERGKVG-----IPSSHSECS 159
            :|||.| |.....|......:|.:|. ||.....|..|:....:...|..|     :|.|.....
Mouse   148 EPGGLG-GSEPPEPSYLDMDSYPEAAVASVVAAGVKPSQTSPELPSEGGTGSGLLLLPPSGGGLP 211

  Fly   160 SNDSMEVSVDSHTGVLTGLSKAT--TTVPHPATAFRNPCGEHRAKTQALRYQHRVNVAAPPKLDK 222
                   |..||..| |.|:..|  ..:|.|.|                  |..:...|.|..:
Mouse   212 -------SAQSHQQV-TSLAPTTRYPALPRPLT------------------QQTLTTQADPSTE- 249

  Fly   223 ERDNVLVVPMVNAYSINNNNNSITTSNNHPSSNNNDDEPLFDTSDLRSIKSDDLLVGVDQKE--- 284
            ||...|.:|:                   |.......                 |:|..:.|
Mouse   250 ERPPALPLPL-------------------PGGEEKAK-----------------LIGQIKPELYQ 278

  Fly   285 ---PAVQR-----------GPIELELSLLYDAPMRKMTVHVMQAKNLPPLGSGQTTHTQVRMLML 335
               |..:|           |.|...|..||.:.  ::.|.::||.:||...|...:...|::.:|
Mouse   279 GTGPGGRRGGGSGEAGAPCGRISFALRYLYGSD--QLVVRILQALDLPAKDSNGFSDPYVKIYLL 341

  Fly   336 PSKKQKLKTKI-RSGENPQYMESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEAYVSFATV 399
            |.:|:|.:||: |...||.:.|:|.. .|...::....|...:|..:|..:..|||:..:...
Mouse   342 PDRKKKFQTKVHRKTLNPIFNETFQF-SVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNL-- 403

  Fly   400 DLEL-----ETNLWLPLEPRNTSSGLGSTSDLLSLARSESAGSTSSMQHGGVSELLLGLSYNGVT 459
             |||     :..||     |:...|....:||                    .||...|.|....
Mouse   404 -LELAEQPPDRPLW-----RDILEGGSEKADL--------------------GELNFSLCYLPTA 442

  Fly   460 GRLSVEIIKGSQFRSLSLNKAPDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAFQVALF 524
            |||:|.|||.|..:::.|....|.|||..::|. |:.:.:.||||::...||.:.|...|.||..
Mouse   443 GRLTVTIIKASNLKAMDLTGFSDPYVKASLISE-GRRLKKRKTSIKKNTLNPTYNEALVFDVAPE 506

  Fly   525 QLNDVTLMISVYAKRHMKKNEMVGWFSLGLNSSGSEEVAHWADVCEMPKGEMLARWHVLVDSXFE 589
            .:.:|.|.|:|.....:..||::|...:|..::......|||::...|: :.:..||.||:   |
Mouse   507 SVENVGLSIAVVDYDCIGHNEVIGVCRVGPEAADPHGREHWAEMLANPR-KPVEHWHQLVE---E 567

  Fly   590 QLGQSSGRSGKAL 602
            :...|..:.||.|
Mouse   568 KTLSSFTKGGKGL 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	34/127 (27%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	43/137 (31%)
Syt3	NP_001107588.1	Cysteine motif. /evidence=ECO:0000269|PubMed:10531343	10..34
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	183..258		21/101 (21%)
		C2A_Synaptotagmin-1-5-6-9-10	297..421	CDD:176031	36/134 (27%)
		C2B_Synaptotagmin-3-5-6-9-10	430..564	CDD:176048	43/135 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1028
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810