Protein Alignment Syt14 and SYT9

DIOPT Version :10

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_011518202.1
• Gene: SYT9 / 143425
• HGNCID: 19265
• Length: 567
• Species: Homo sapiens
• Alignment Length: 364
• Identity: 92/364 - (25%)
• Similarity: 160/364 - (43%)
• Gaps: 60/364 - (16%)

  Fly   246 TTSNNHPSSNN--NDDEPLFDTSDLRSIKSDDLLVGVDQKEPAVQR-----------------GP 291
            |:|..|.|...  |...|.|   :::.::..:.|.|:.:.:|.:.:                 |
Human   162 TSSARHNSIRRQLNLSNPDF---NIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACG- 222

  Fly   292 IELELSLLYDAPMRKMTVHVMQAKNLPPLGSGQTTHTQVRMLMLPSKKQKLKTKI-RSGENPQYM 355
             :|...|.||..:.::.|.:.:|.|||......|:...|::.:||.:|.|.:||: |...||.:.
Human   223 -KLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFD 286

  Fly   356 ESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEAYVS--FATVDLELETNLWLPLEPRNTSS 418
            |.||. .|...|:....|...:|..:|..:..|||:..|.  ....|...|..||..:|
Human   287 EVFLF-PVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIE------ 344

  Fly   419 GLGSTSDLLSLARSESAGSTSSMQHGGVSELLLGLSYNGVTGRLSVEIIKGSQFRSLSLNKAPDT 483
              ..|:|.:.|                 .||:..|.|....|||::.|||....:::.:..|.|.
Human   345 --YVTNDNVDL-----------------GELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDP 390

  Fly   484 YVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAFQVALFQLNDVTLMISVYAKRHMKKNEMVG 548
            |||:.::.. |:.:.:.|||.:|...||::.|...|.|....::.:.|.|:|.....:..||::|
Human   391 YVKVSLMCD-GRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIG 454

  Fly   549 WFSLGLNSSGSEEVA--HWADVCEMPKGEMLARWHVLVD 585
            ...:|   :.:|.:.  ||:::...|: :.:|.||.||:
Human   455 VCQVG---NEAERLGRDHWSEMLSYPR-KPIAHWHSLVE 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	36/124 (29%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	39/139 (28%)
SYT9	XP_011518202.1	C2	221..345	CDD:472691	38/134 (28%)
		C2B_Synaptotagmin-3-5-6-9-10	354..487	CDD:176048	39/137 (28%)