DRSC/TRiP Functional Genomics Resources

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Protein Alignment Syt14 and Sytl4

DIOPT Version :9

Sequence 1:NP_001262249.1 Gene:Syt14 / 40544 FlyBaseID:FBgn0261086 Length:648 Species:Drosophila melanogaster
Sequence 2:NP_536335.1 Gene:Sytl4 / 140594 RGDID:620204 Length:672 Species:Rattus norvegicus


Alignment Length:337 Identity:76/337 - (22%)
Similarity:143/337 - (42%) Gaps:46/337 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   293 ELELSLLYDAPMRKMTVHVMQAKNLPPLGSG-QTTHTQVRMLMLPSKKQ--KLKTKI-RSGENPQ 353
            ::..||.::...:.:.:||.:...|...... :.::..|:..:||.|.:  |.||.| |...||.
  Rat   360 KIAFSLKFEQKTQTLVIHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPL 424

  Fly   354 YMESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEAYVSFATVDLELETNLWLPLEPR---N 415
            |.|:| .:.::...:....|:..::...|..:...:|||.|...:..|:.:.:..|||..:   .
  Rat   425 YDETF-RYEISESLLAQRTLQFSVWHHGRFGRNTFLGEAEVHMDSWKLDKKLDHCLPLHGKISTE 488

  Fly   416 TSSGLGSTSDLLSLARSESAGSTSSMQHGGVSELLLG----LSYNGVTGRLSVEIIKGSQFRSLS 476
            :|.||.:....|.:          |:::...|:|.:|    .|..|..|.|.|.|.:.....:..
  Rat   489 SSPGLPAHKGELVV----------SLKYIPASKLPVGGDRKKSKGGEGGELQVWIKEAKNLTAAK 543

  Fly   477 LNKAPDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAFQ-VALFQLNDVTLMISVYAKRH 540
            .....|::||..:: .:..:.|:.||.:.:...||.:..||.:. |.|..|..:.|.::|:.:..
  Rat   544 SGGTSDSFVKGYLL-PMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREP 607

  Fly   541 MKKNEMVGWFSLGLNSS-GSEEVAHWADVCEMPKGEMLARWHVLVDSXFEQLGQSSG-------- 596
            :..|:.:|...||:.:. .|.||..|.|    ..||.::.|        :::.|..|        
  Rat   608 LASNDFLGGVRLGVGTGISSGEVVDWMD----STGEEVSLW--------QKMRQYPGSWAEGTLQ 660

  Fly   597 -RSGKALRKLSL 607
             ||....:||.:
  Rat   661 LRSSMVKQKLGV 672

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Syt14NP_001262249.1 C2A_Synaptotagmin-14_16 291..413 CDD:176035 29/123 (24%)
C2B_Synaptotagmin-14_16 446..584 CDD:176053 36/143 (25%)
Sytl4NP_536335.1 FYVE_Slp4 58..107 CDD:277303
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 199..222
C2A_SLP-4_5 358..482 CDD:175995 28/122 (23%)
C2B_SLP_1-2-3-4 497..662 CDD:175987 40/187 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1028
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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