Protein Alignment Syt14 and Syt17

DIOPT Version :10

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: NP_001390574.1
• Gene: Syt17 / 110058
• MGIID: 104966
• Length: 474
• Species: Mus musculus
• Alignment Length: 569
• Identity: 119/569 - (20%)
• Similarity: 211/569 - (37%)
• Gaps: 169/569 - (29%)

  Fly    46 CFHYRHAINCCDERHLAVKCVQKITRKRRYENTSSDSEEDILRRL--------RWHQQHQLGEKP 102
            |.|      ||               :|.||::...|.||.:..|        .|....:..:|.
Mouse    27 CQH------CC---------------QRCYESSCCQSSEDEVEILGPFPAQTPPWLMASRSNDKD 70

  Fly   103 GGYGLGISQAN--PLTAQSFNYHQAGASADLQRVTVS-------------RDPLAIAERGKVGIP 152
            |.   .:..|:  |||.::.:.....:|:|..:.|.|             ..||...:..:.|:.
Mouse    71 GD---SVHTASDVPLTPRTNSPDGRRSSSDTSKSTYSLTRRISSLDSRRPSSPLIDIKPVEFGVL 132

  Fly   153 SSHSECSSNDSMEVSVDSHTGVLTGLSKATTTVPHPATAFRNPCGEHRAKTQALRYQHRVNVAAP 217
            |:..|     |::.||         |.:..|    |...||             :::.|:
Mouse   133 SAKKE-----SIQPSV---------LRRTYT----PDDYFR-------------KFEPRL----- 161

  Fly   218 PKLDKERDNVLVVPMVNAYSINNNNNSITTSNNHPSSNNNDDEPLFDTSDLRSIKSDDLLVGVDQ 282
                              ||:::|                       ..|:.|:..::::
Mouse   162 ------------------YSLDSN-----------------------LDDVDSLTDEEIM----- 180

  Fly   283 KEPAVQRGPIELELSLLYDAPMRKMTVHVMQAKNLPPL----GSGQT---THTQVRMLMLPSKKQ 340
              ...|.|  .|..|..||.....:||.|::|::|||.    ||.|.   ::..|::.:||.:|.
Mouse   181 --SKYQLG--MLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKN 241

  Fly   341 KLKTKI-RSGENPQYMESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEAYVSFATVDLELE 404
            ..:|.: |..:.|.:.|.:.. .:...:.....|.:.:...::..:..:||:..|....|||...
Mouse   242 SKQTGVKRKTQKPVFEERYTF-EIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVAVPLCEVDLVKG 305

  Fly   405 TNLWLPLEPRNTSSGLGSTSDLLSLARSESAGSTSSMQHGGVSELLLGLSYNGVTGRLSVEIIKG 469
            .:.|..|.|                         ||.....:.||||.|:|....|||:|:||:.
Mouse   306 GHWWKALIP-------------------------SSQNEVELGELLLSLNYLPSAGRLNVDIIRA 345

  Fly   470 SQFRSLSLNKAPDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAFQVALFQLNDVTLMIS 534
            .|.....:::..|.:||:.:|..: :.:...|||..||..:|.:.|:|:|:|...:|.:.:|:.:
Mouse   346 KQLLQTDVSQGSDPFVKIQLVHGL-KLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFT 409

  Fly   535 VYAKRHMKKNEMVGWFSLGLNSSGSEEVAHWADVCEMPKGEMLARWHVL 583
            |:.......|:.:|...:|..|||..|..||..:....: ..:.:||.|
Mouse   410 VFGHNMKSSNDFIGRIVIGQYSSGPSESNHWRRMLNTHR-TAVEQWHSL 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	31/129 (24%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	42/138 (30%)
Syt17	NP_001390574.1	C2A_Synaptotagmin-15-17	186..314	CDD:176036	32/130 (25%)
		C2B_Synaptotagmin-17	323..457	CDD:176055	41/135 (30%)