Protein Alignment Syt14 and syt3

DIOPT Version :10

• Sequence 1: NP_001262249.1
• Gene: Syt14 / 40544
• FlyBaseID: FBgn0261086
• Length: 648
• Species: Drosophila melanogaster
• Sequence 2: XP_005164031.1
• Gene: syt3 / 100000615
• ZFINID: ZDB-GENE-090601-1
• Length: 566
• Species: Danio rerio
• Alignment Length: 617
• Identity: 127/617 - (20%)
• Similarity: 216/617 - (35%)
• Gaps: 178/617 - (28%)

  Fly    17 TIEVTTLLGAFFGVLVLLLLLFLFISRKCCFHYRHAINCCDERHLAVKCVQKITRKRRYENTSSD 81
            ::.:.:::..|.|  ::||.:.||:|.|.|:
Zfish    52 SVSLLSVIVTFCG--IVLLSVSLFVSWKLCW---------------------------------- 80

  Fly    82 SEEDILRRLRWHQQH------QLGEKPGGYGLG----------------------ISQANPLTAQ 118
                    |.|..:.      ..|..|||.|||                      .|...|..:|
Zfish    81 --------LPWRDKEGGGLSLTSGLLPGGAGLGGVGGGGGASLLPPLLQRKDTHSSSSLYPTLSQ 137

  Fly   119 SFNYHQAGASADLQRVTVSRDPLAIAERGKVGIPSSHSECSSNDSMEVSVDSHTGVLTGLSKATT 183
            ...:|.  ..:|:..|....   .:...|.||.|....|.|..|     :||:......|..:.|
Zfish   138 QGQHHP--HFSDVMGVEGGG---GLVVGGVVGGPQEMQEHSYLD-----MDSYPNNAATLKLSQT 192

  Fly   184 TVPHPATAFRNPCGEHRAKTQALRYQH-RVNVAAPPKLDKERDNVLVVPMVNAYSINNNNNSITT 247
            :...|      |..|..:..:.|...| :..|...||           ||.:..|
Zfish   193 SPELP------PATEGGSAAKDLPNAHSQQQVTTRPK-----------PMTHQLS---------- 230

  Fly   248 SNNHPSSNNNDDEPLFDTSDLRSIKSDDLLVGVDQKEPAVQR---------------GPIELELS 297
                             :.|....:..:.|..:.|.:|.:.|               |.|...|.
Zfish   231 -----------------SPDFHGEEKSEQLTSIGQIKPELYRLRQGDQGDGKQGNNCGKISFLLR 278

  Fly   298 LLYDAPMRKMTVHVMQAKNLPPLGSGQTTHTQVRMLMLPSKKQKLKTKI-RSGENPQYMESFLLH 361
            ..::.  .::.|.:::|.:||...:...:...|::.:||.:|:|.:||: |...||.:.|:|..
Zfish   279 YAFNT--EQLVVKILKALDLPAKDANGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQF- 340

  Fly   362 RVNPEDVNNMGLRVRLYGCERLRKERLIGEAYVSFATVDLELETN---LWLPLEPRNTSSGLGST 423
            .|...:::...|...:|..:|..:..|||:..|. ..:|....|.   :|     |:...|....
Zfish   341 GVPLAELHARKLHFSVYDFDRFSRHDLIGQVVVD-NLLDFSEGTGEKPIW-----RDIVEGTAEK 399

  Fly   424 SDLLSLARSESAGSTSSMQHGGVSELLLGLSYNGVTGRLSVEIIKGSQFRSLSLNKAPDTYVKMV 488
            :||                    .||...|.|....|||:|.|||.:..:::.|....|.|||..
Zfish   400 ADL--------------------GELNFSLCYLPTAGRLTVTIIKATNLKAMDLTGFSDPYVKAS 444

  Fly   489 MVSSIGQEISRAKTSIRRGQPNPLFKETFAFQVALFQLNDVTLMISVYAKRHMKKNEMVGWFSLG 553
            :|.. |:.:.:.||||::...||.:.|...|.:....:..|:|:|:|.....:..||::|...:|
Zfish   445 LVCE-GRRLKKRKTSIKKNTLNPTYNEALVFDIPNENIESVSLIIAVMDYDCIGHNEVIGMCRMG 508

  Fly   554 LNSSGSEEVAHWADVCEMPKGEMLARWHVLVD 585
            .::.|... .||..:...|: :.:..||.||:
Zfish   509 SDADGPGR-EHWTAMLANPR-KPIEHWHQLVE 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syt14	NP_001262249.1	C2A_Synaptotagmin-14_16	291..413	CDD:176035	29/125 (23%)
		C2B_Synaptotagmin-14_16	446..584	CDD:176053	40/137 (29%)
syt3	XP_005164031.1	C2A_Synaptotagmin-1-5-6-9-10	269..394	CDD:176031	31/133 (23%)
		C2B_Synaptotagmin-3-5-6-9-10	403..536	CDD:176048	40/135 (30%)