DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Suv3 and C08F8.2

DIOPT Version :9

Sequence 1:	NP_001303458.1	Gene:	Suv3 / 40543	FlyBaseID:	FBgn0037232	Length:	763	Species:	Drosophila melanogaster
Sequence 2:	NP_001040912.1	Gene:	C08F8.2 / 178022	WormBaseID:	WBGene00007444	Length:	719	Species:	Caenorhabditis elegans

Alignment Length:	691	Identity:	319/691 - (46%)
Similarity:	448/691 - (64%)	Gaps:	21/691 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 SRKKPET-----NLSTLFKPVQV-HAYVDSEDVGSELSGKLEKAELLKILNKFTQRREIKSLCNE 99
            ||:|..:     .:..:.:|.:| |....:..:| |..|.|:...:...|::|.:|..::.|..|
Worm    34 SRRKRNSVRKTATIEDIVEPRKVKHVTQTAAGMG-EWIGSLDNTNIHMSLDEFMRRPMVRQLAKE 97

  Fly   100 NGLDDYLQQQAFGSFRRFCIEAENLPVD--LHITFSDITQGAGHIDDIFPYFLRHAKTVFPHLDC 162
            ||::|.|..::|.|||.:|...:...||  |.|..|||::|....:.::|:||.|||.|||||:.
Worm    98 NGINDKLFMRSFKSFREYCTPEDLNSVDPGLLILLSDISKGTKDCEMLYPFFLDHAKQVFPHLEA 162

  Fly   163 MDDLKKISDLRQPANWYSNARAITRKIVFHAGPTNSGKTYHAMERYLSAKTGVYCGPLKLLATEV 227
            ||||:.||||.:|.|||..||::||||.||||||||||||||::|:..||:.|:||||||||.||
Worm   163 MDDLRIISDLTRPHNWYPEARSVTRKIFFHAGPTNSGKTYHALKRFGEAKSAVFCGPLKLLAAEV 227

  Fly   228 YNKANERGTPCDLVTGEERKFGISESLPANHVACTVEMTSVNTPYEVAVIDEIQQIRDPQRGWAW 292
            :::.||.|.||||||||||:|......|:.|::.||||.|.....|||||||||.:||.||||||
Worm   228 FHRTNELGIPCDLVTGEERRFAKDNHHPSQHLSSTVEMLSTQMRVEVAVIDEIQMLRDEQRGWAW 292

  Fly   293 TRAFLGLIADEVHVCGEPGALDLLQKICETTGETVEVRLYDRLTELTVENTALGSLDNIVPGDCI 357
            |||.||..|||:|:||||.|:|:::|:.|..|||||||.|:|.:.|.:.:.|:.|..||.|||||
Worm   293 TRALLGAAADEIHLCGEPAAIDIVKKLLEPIGETVEVRYYERKSPLAIADKAIESYSNIEPGDCI 357

  Fly   358 VCFSKHDIYTVSREIEARGKEVAVIYGGLPPGTKLAQAAKFNDPANSCKVMVATDAIGMGLNLSI 422
            |||||..|:..|:::|..|.:.|||||.||||||||||||||||.:.|.|:||||||||||||:|
Worm   358 VCFSKRSIFFNSKKLEENGIKPAVIYGDLPPGTKLAQAAKFNDPDDECNVLVATDAIGMGLNLNI 422

  Fly   423 RRIIFYSLIKPSMNERGEREIDTISVSSALQIAGRAGRFRTQWEHGYVTAFKSEDLQTLQRILAR 487
            ||:||.|.         .|:.:.:...:|||||||||||.|.:.:|..|..:.|||.||:.||:.
Worm   423 RRVIFNSC---------TRQTELLPTYAALQIAGRAGRFGTAYANGVATTMRKEDLGTLKAILSE 478

  Fly   488 TPEPIKQAGLHPTADQIELYAYHLPSSSLSNLMDIFVNLCTVDDSLYFMCNIEDFKFLAEMIQHV 552
            ..|||...|:.||.||||.:::|||.:|...|:|:||::|:|.|. :|:|.:.|.:.||.:|..:
Worm   479 KIEPIANVGIAPTYDQIETFSFHLPQASFVRLLDLFVSVCSVSDH-FFICTVYDMRELAVLIDQI 542

  Fly   553 ALPLRARYVFCCAPINRKMPFVCSMFLKVARQYSRNEPITFDFIKKNCGWPFKLPKTILDLVHLE 617
            .|||:.||.||.:|:|.:.....::|:|:||::|..:.:|::::.....||.|...|:.:|..||
Worm   543 PLPLKVRYTFCTSPLNTEDKRTSAVFVKMARRFSTGQALTYEWLIDMLEWPPKPATTLNELSLLE 607

  Fly   618 AVFDVMDLYLWLSYRFMDLFPEAAYVRDAQKELDEIIQQGVFQITRLLK--NTEASQDGETSNYA 680
            ..::::|.|:|||.||.|:.|:...||:|.|.||.:||:||.....||.  .||:...|.:.:..
Worm   608 QNYEILDQYMWLSMRFPDMLPDEPRVREASKHLDSMIQEGVESFMSLLSVGATESKAAGSSKSSE 672

  Fly   681 IRRITHVKEPRLPSLSRGRLTERLLAQGLLTPGMLSELRKE 721
            .:|....|..|.....|..:.|.||.:..::...|.:||:|
Worm   673 GKRENPSKSEREKPNKRSSILEALLKRADISEDDLEQLREE 713

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Suv3	NP_001303458.1	DEXDc	193..323	CDD:238005	81/129 (63%)
		SrmB	195..507	CDD:223587	180/311 (58%)
		HELICc	<357..461	CDD:238034	61/103 (59%)
		SUV3_C	614..657	CDD:289293	19/42 (45%)
C08F8.2	NP_001040912.1	Suv3_N	49..166	CDD:407948	42/117 (36%)
		DEXQc_Suv3	187..332	CDD:350671	93/144 (65%)
		SF2_C_suv3	336..465	CDD:350192	75/137 (55%)
		Suv3_C_1	536..576	CDD:407979	15/39 (38%)
		SUV3_C	606..649	CDD:403643	20/42 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162577
Domainoid	1	1.000	240	1.000	Domainoid score	I1264
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2386
Inparanoid	1	1.050	611	1.000	Inparanoid score	I494
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45841
OrthoDB	1	1.010	-	-		D1106167at2759
OrthoFinder	1	1.000	-	-		FOG0003663
OrthoInspector	1	1.000	-	-		oto19807
orthoMCL	1	0.900	-	-		OOG6_101922
Panther	1	1.100	-	-	LDO	PTHR12131
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1417
SonicParanoid	1	1.000	-	-		X3030
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.940