DRSC/TRiP Functional Genomics Resources

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Protein Alignment Vps24 and Chmp2a

DIOPT Version :9

Sequence 1:NP_001303457.1 Gene:Vps24 / 40542 FlyBaseID:FBgn0037231 Length:223 Species:Drosophila melanogaster
Sequence 2:NP_001347659.1 Gene:Chmp2a / 68953 MGIID:1916203 Length:222 Species:Mus musculus


Alignment Length:234 Identity:58/234 - (24%)
Similarity:116/234 - (49%) Gaps:31/234 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 LFGRTPSKDPKEQVQEWTHKIRKEGNQLDRQIRSIQREEEKVKRSLKQAAQKNDRDTCVILAKEI 67
            ||||  .|.|:|.:::....:.:...:|||:.:.::.:|:|:...:|:.|::...|...|:||::
Mouse     4 LFGR--RKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDL 66

  Fly    68 VNARKAINRIYTSKAHLNSIQMQMKNQLSTLRVAGSLQKSTEVLQAMQSLVRYPELAGIMRDMSK 132
            |..|:.:.:....:|::.::.::::...|...:|.:::..|:.:..|...::.|::..||.:..:
Mouse    67 VRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFER 131

  Fly   133 EMMKAGIIEEMLDETMDSLEESEELEEEASKEVDKVLWEI-------------TDGKLGEAPLPP 184
            :.....:.|||:::.:|.....||.|||:...|.:||.|:             |.|.|.      
Mouse   132 QAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPSTGGSLS------ 190

  Fly   185 EATPADKASASA-ARVEAEQDDEEGEELQEMQSRLASLR 222
            .|....||.|:| |..:|:.|.||         ||.:||
Mouse   191 VAAGGKKAEATASALADADADLEE---------RLKNLR 220

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Vps24NP_001303457.1 Snf7 18..187 CDD:281366 37/181 (20%)
Chmp2aNP_001347659.1 Snf7 17..185 CDD:397437 34/167 (20%)
Interaction with VPS4B. /evidence=ECO:0000250 56..222 44/180 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 179..198 4/24 (17%)
MIT-interacting motif 210..220 5/18 (28%)
Interaction with VTA1. /evidence=ECO:0000250 217..222 2/4 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5491
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53529
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.820

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