Protein Alignment Vps24 and Chmp2a

DIOPT Version :10

• Sequence 1: NP_649451.1
• Gene: Vps24 / 40542
• FlyBaseID: FBgn0037231
• Length: 223
• Species: Drosophila melanogaster
• Sequence 2: NP_081161.1
• Gene: Chmp2a / 68953
• MGIID: 1916203
• Length: 222
• Species: Mus musculus
• Alignment Length: 234
• Identity: 58/234 - (24%)
• Similarity: 116/234 - (49%)
• Gaps: 31/234 - (13%)

  Fly     3 LFGRTPSKDPKEQVQEWTHKIRKEGNQLDRQIRSIQREEEKVKRSLKQAAQKNDRDTCVILAKEI 67
            ||||  .|.|:|.:::....:.:...:|||:.:.::.:|:|:...:|:.|::...|...|:||::
Mouse     4 LFGR--RKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDL 66

  Fly    68 VNARKAINRIYTSKAHLNSIQMQMKNQLSTLRVAGSLQKSTEVLQAMQSLVRYPELAGIMRDMSK 132
            |..|:.:.:....:|::.::.::::...|...:|.:::..|:.:..|...::.|::..||.:..:
Mouse    67 VRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFER 131

  Fly   133 EMMKAGIIEEMLDETMDSLEESEELEEEASKEVDKVLWEI-------------TDGKLGEAPLPP 184
            :.....:.|||:::.:|.....||.|||:...|.:||.|:             |.|.|.
Mouse   132 QAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPSTGGSLS------ 190

  Fly   185 EATPADKASASA-ARVEAEQDDEEGEELQEMQSRLASLR 222
            .|....||.|:| |..:|:.|.||         ||.:||
Mouse   191 VAAGGKKAEATASALADADADLEE---------RLKNLR 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps24	NP_649451.1	Snf7	18..187	CDD:460896	37/181 (20%)
Chmp2a	NP_081161.1	Snf7	17..185	CDD:460896	34/167 (20%)
		Interaction with VPS4B. /evidence=ECO:0000250	56..222		44/180 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	179..198		4/24 (17%)
		MIT-interacting motif	210..220		5/18 (28%)
		Interaction with VTA1. /evidence=ECO:0000250	217..222		2/4 (50%)