Protein Alignment Vps24 and CHMP2B

DIOPT Version :10

• Sequence 1: NP_649451.1
• Gene: Vps24 / 40542
• FlyBaseID: FBgn0037231
• Length: 223
• Species: Drosophila melanogaster
• Sequence 2: NP_001397706.1
• Gene: CHMP2B / 25978
• HGNCID: 24537
• Length: 245
• Species: Homo sapiens
• Alignment Length: 195
• Identity: 50/195 - (25%)
• Similarity: 110/195 - (56%)
• Gaps: 5/195 - (2%)

  Fly    16 VQEWTHKIRKEGNQLDRQIRSIQREEEKVKRSLKQAAQKNDRDTCVILAKEIVNARKAINRIYTS 80
            ::|...::|.....:.|...:::::|::::..:|:.|:..:::.|.:|||::|:.||...|.:..
Human    46 IKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACKVLAKQLVHLRKQKTRTFAV 110

  Fly    81 KAHLNSIQMQMKNQLSTLRVAGSLQKSTEVLQAMQSLVRYPELAGIMRDMSKEMMKAGIIEEMLD 145
            .:.:.|:..|.|...|.:::||::..:.:.:||:...:...:....|::..||.||..:.|||::
Human   111 SSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQNFQKENMKMEMTEEMIN 175

  Fly   146 ETMDSLEESEELEEEASKEVDKVLWEI---TDGKLGEAPLPPEATPADKASASAARVEAEQDDEE 207
            :|:|.:.:..:.|||:...|::||.||   ..||:.:||....:.|:  ||.|.|.:..|:.:.:
Human   176 DTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKAPSAARSLPS--ASTSKATISDEEIERQ 238

  Fly   208  207
            Human   239  238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps24	NP_649451.1	Snf7	18..187	CDD:460896	44/171 (26%)
CHMP2B	NP_001397706.1	Snf7	48..217	CDD:460896	44/168 (26%)