DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vps24 and C01A2.4

DIOPT Version :9

Sequence 1:	NP_001303457.1	Gene:	Vps24 / 40542	FlyBaseID:	FBgn0037231	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_001369988.1	Gene:	C01A2.4 / 182050	WormBaseID:	WBGene00007216	Length:	207	Species:	Caenorhabditis elegans

Alignment Length:	226	Identity:	59/226 - (26%)
Similarity:	112/226 - (49%)	Gaps:	22/226 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGLFGRTPSKDPKEQVQEWTHKIRKEGNQLDRQIRSIQREEEKVKRSLKQAAQKNDRDTCVILAK 65
            |.:|.:   .||||..:....::||....|:...|.:.|.|:::::.:|:.|.|...|....|||
Worm     1 MNIFSK---PDPKELERANKRELRKTNRDLESDRRQMDRREKELEQEIKKLAAKGHNDAARHLAK 62

  Fly    66 EIVNARKAINRIYTSKAHLNSIQMQMKNQLSTLRVAGSLQKSTEVLQAMQSLVRYPELAGIMRDM 130
            ::|..|....:.....|.::.:|.|..:..|..::..::..:.:.::||.:.:...::|..||:.
Worm    63 QLVQLRNQKTKSIGMSARISGVQAQNSHMQSMAKMGSAMGTTVKTMKAMNAQMPLEKVAANMREF 127

  Fly   131 SKEMMKAGIIEEMLDETMDSLEESEELEEEASKEVDKVLWEI---TDGKLGEAPLPPEATPADKA 192
            .....|.|:.|||:::|:||:.::....:|....|::||.||   .:.||...|..|     .|.
Worm   128 QMAQEKMGLTEEMMNDTLDSILDAPGDADEQDAIVNQVLDEIGIEMNSKLANVPALP-----TKV 187

  Fly   193 SASAARVEAEQDDEEGEELQEMQSRLASLRS 223
            |::|   .|:.||        ::::||.|||
Worm   188 SSTA---PADFDD--------LEAQLARLRS 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vps24	NP_001303457.1	Snf7	18..187	CDD:281366	42/171 (25%)
C01A2.4	NP_001369988.1	Snf7	16..185	CDD:397437	42/173 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5491
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53529
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820