DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Vps24 and vps-24

DIOPT Version :9

Sequence 1:	NP_001303457.1	Gene:	Vps24 / 40542	FlyBaseID:	FBgn0037231	Length:	223	Species:	Drosophila melanogaster
Sequence 2:	NP_494919.1	Gene:	vps-24 / 173863	WormBaseID:	WBGene00020866	Length:	208	Species:	Caenorhabditis elegans

Alignment Length:	228	Identity:	116/228 - (50%)
Similarity:	163/228 - (71%)	Gaps:	27/228 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGLFGRTPSKDPKEQVQEWTHKIRKEGNQLDRQIRSIQREEEKVKRSLKQAAQKNDRDTCVILAK 65
            |||||:  .|||||:|:|...|:|:|...||||:.||||||:||.:.:|:||:|.|:|.|:||||
Worm     1 MGLFGK--KKDPKEEVRELQRKMRQEMRSLDRQVYSIQREEQKVTKEIKEAAKKGDKDVCLILAK 63

  Fly    66 EIVNARKAINRIYTSKAHLNSIQMQMKNQLSTLRVAGSLQKSTEVLQAMQSLVRYPELAGIMRDM 130
            .::.:||||::|:.|||.:||:.|.|:.||:|:|:||||||||||:::||.||:.||:...||:|
Worm    64 SMIQSRKAISKIHVSKAQINSVIMCMQEQLATIRMAGSLQKSTEVMKSMQQLVKVPEIMKTMREM 128

  Fly   131 SKEMMKAGIIEEMLDETMDSLEESEELEEEASKEVDKVLWEITDGKLGEAPLPPEA------TPA 189
            |.||||.||||||::||::|:|.: .|||:|.:||:.:|||:|.|:||:|||..::      |||
Worm   129 SAEMMKLGIIEEMIEETLESVEPA-GLEEKAQEEVENILWEVTQGELGKAPLAVKSNIGGVVTPA 192

  Fly   190 DKASASAARVEAEQDDEEGEELQEMQSRLASLR 222
                         .:|.||     |..|||.||
Worm   193 -------------VEDFEG-----MAQRLAELR 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vps24	NP_001303457.1	Snf7	18..187	CDD:281366	93/174 (53%)
vps-24	NP_494919.1	Snf7	16..180	CDD:304451	92/164 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156093
Domainoid	1	1.000	191	1.000	Domainoid score	I1911
eggNOG	1	0.900	-	-		E1_COG5491
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6368
Inparanoid	1	1.050	213	1.000	Inparanoid score	I2353
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53529
OrthoDB	1	1.010	-	-		D1418709at2759
OrthoFinder	1	1.000	-	-		FOG0004091
OrthoInspector	1	1.000	-	-		oto19130
orthoMCL	1	0.900	-	-		OOG6_103236
Panther	1	1.100	-	-	LDO	PTHR10476
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1644
SonicParanoid	1	1.000	-	-		X5117
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.840