DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MP1 and Prss32

DIOPT Version :9

Sequence 1:	NP_001303421.1	Gene:	MP1 / 40541	FlyBaseID:	FBgn0027930	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_081496.2	Gene:	Prss32 / 69814	MGIID:	1917064	Length:	334	Species:	Mus musculus

Alignment Length:	326	Identity:	95/326 - (29%)
Similarity:	138/326 - (42%)	Gaps:	79/326 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 GNHPQPTQTTKPTKRSGTKLLPMAPNCGE-NFGDRVVGGNETTKREFPWMALIEYTKPGNVKGHH 167
            |:...||.:..|:..:|.:.:.:...||. ....|:|.|.:.....:||...:...     ..|.
Mouse    19 GSEVLPTDSDSPSTTTGRRSIDLDSVCGRPRTSGRIVSGQDAQLGRWPWQVSVREN-----GAHV 78

  Fly   168 CGGSLINHRYVLTAAHC----------------VSAIPSDWELTGVRLGEWDASTNPDCTVGKNG 216
            ||||||...:|||||||                :|:.|.|
Mouse    79 CGGSLIAEDWVLTAAHCFNQGQSLSIYTVLLGTISSYPED------------------------- 118

  Fly   217 RRDCNEPYVDYPVEERIPHPQYPGNSRDQLNDIALLRLRDEVQYSDFILPVCLPTLASQHNNIFL 281
                |||.....|.:.|.||.|..:.... .||||::|...:.::|::||||||   ...:.:..
Mouse   119 ----NEPKELRAVAQFIKHPSYSADEHSS-GDIALVQLASPISFNDYMLPVCLP---KPGDPLDP 175

  Fly   282 GRKVVVAGWGRTETN------FTSNIKLKAELDTVPTSECNQRYATQRRTVTTKQ-------MCA 333
            |....|.|||...||      ||..   :.::..:....||..|  |..::...:       :||
Mouse   176 GTMCWVTGWGHIGTNQPLPPPFTLQ---ELQVPLIDAETCNTYY--QENSIPGTEPVILEGMLCA 235

  Fly   334 GGVEG-VDSCRGDSGGPLLLEDYSNGNSNYYIAGVVSYGPTPCGLKGWPGVYTRVEAYLNWIENN 397
            |..|| .|:|.|||||||:.:.    |..:..|||||:| :.|.|...|||||.|..|::||:|.
Mouse   236 GFQEGKKDACNGDSGGPLVCDI----NDVWIQAGVVSWG-SDCALFKRPGVYTNVSVYISWIQNT 295

  Fly   398 V 398
            :
Mouse   296 M 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MP1	NP_001303421.1	CLIP	29..91	CDD:288855
		Tryp_SPc	137..394	CDD:214473	85/286 (30%)
		Tryp_SPc	138..397	CDD:238113	86/288 (30%)
Prss32	NP_081496.2	Tryp_SPc	53..292	CDD:214473	85/286 (30%)
Prss32	NP_081496.2	Tryp_SPc	54..295	CDD:238113	86/288 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810