DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MP1 and Prss41

DIOPT Version :9

Sequence 1:	NP_001303421.1	Gene:	MP1 / 40541	FlyBaseID:	FBgn0027930	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_001128559.1	Gene:	Prss41 / 681033	RGDID:	1584711	Length:	324	Species:	Rattus norvegicus

Alignment Length:	311	Identity:	103/311 - (33%)
Similarity:	144/311 - (46%)	Gaps:	84/311 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 KRSGTKLLPMAPNCG--ENFGDRVVGGNETTKREFPWMALIEYTKPGNVKGHHCGGSLINHRYVL 179
            |.:..|||.|.  ||  .:...|:|||.|:.:..:||.|.:...     |.|.|||||::||:||
  Rat    34 KNTDIKLLSMP--CGRRNDIRSRIVGGIESVRGRWPWQASLRLR-----KFHRCGGSLLSHRWVL 91

  Fly   180 TAAHCVSAI--PSDWELTGVRLGE-------WDASTNPDCTVGKNGRRDCNEPYVDYPVEERIPH 235
            |||||....  |..|.   |:||:       |    |.:...|:            |.|::.|.
  Rat    92 TAAHCFRKFLDPKKWT---VQLGQLTSKPSFW----NREAFSGR------------YRVKDIII- 136

  Fly   236 PQYPGNSRDQL--NDIALLRLRDEVQYSDFILPVC-LPTLA-SQHNNIFLGRKVVVAGWGRTETN 296
                 ||.|:|  :|:|||||...|.|:.||.||| ||:.: |||.     .:..|.|||
  Rat   137 -----NSEDKLKYHDLALLRLASSVTYNKFIQPVCVLPSASMSQHQ-----PRCWVTGWG----- 186

  Fly   297 FTSNIKLKAELDTVP--------------TSECNQ--RYATQRRTVTTKQMCAGGVEG-VDSCRG 344
                 .|:.:|..:|              .|.|.:  .:|::...:|....|||..:| .|:|.|
  Rat   187 -----ALQEDLKPLPPPYHLREVQVTVLNLSRCQELFSFASRYHLITRDVFCAGAEDGSADTCSG 246

  Fly   345 DSGGPLLLEDYSNGNSNYYIAGVVSYGPTPCGLKGWPGVYTRVEAYLNWIE 395
            ||||||:    .|.:..:|..|:||.| ..||....||:||.|..:.:||:
  Rat   247 DSGGPLV----CNMDGLWYQIGIVSRG-VGCGRPKLPGIYTNVSHHYDWIK 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MP1	NP_001303421.1	CLIP	29..91	CDD:288855
		Tryp_SPc	137..394	CDD:214473	94/286 (33%)
		Tryp_SPc	138..397	CDD:238113	95/288 (33%)
Prss41	NP_001128559.1	Tryp_SPc	54..291	CDD:214473	94/286 (33%)
Prss41	NP_001128559.1	Tryp_SPc	55..292	CDD:238113	94/286 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910