DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MP1 and CG4815

DIOPT Version :9

Sequence 1:	NP_001303421.1	Gene:	MP1 / 40541	FlyBaseID:	FBgn0027930	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_651607.1	Gene:	CG4815 / 43360	FlyBaseID:	FBgn0039568	Length:	265	Species:	Drosophila melanogaster

Alignment Length:	289	Identity:	67/289 - (23%)
Similarity:	106/289 - (36%)	Gaps:	83/289 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 FGDRVVGGNETTKREFPWMALIEYTKPGNVKGHHCGGSLINHRYVLTAAHCVSAI-PSDWELTGV 197
            |..|:..|.:||......:.:..:    |.:...|..:|:..|::||||||...: .|.:.:.|.
  Fly    31 FHPRIYNGIKTTVESLGGVGIQLF----NGRKLVCSATLLTPRHILTAAHCFENLNRSKFHVIGG 91

  Fly   198 RLGEWDASTNPDCTVGKNGRRDCNEPYVDYPVEERIPHPQYPGNSRDQLNDIALLR----LRDE- 257
            :..|:....|   ...||..           :..:| ||:|.  ....:.|:|:.:    ||.:
  Fly    92 KSAEFTWHGN---NFNKNKL-----------IRVQI-HPKYA--KMKFIADVAVAKTKYPLRSKY 139

  Fly   258 VQYSDFILPVCLPTLASQHNNIFLGRKVVVAGWG---------RTETNFTSNIKLKAELDTVPTS 313
            :.|:.....|..|.           .|::.||||         |.:| |.|     .::..|...
  Fly   140 IGYAQLCRSVLHPR-----------DKLIAAGWGFEGGVWDESRKKT-FRS-----MKVGIVSKR 187

  Fly   314 ECNQRYATQRRTVTTKQMCAGGVEGVDSCRGDSGGPLLLEDYSNGNSNYYIAGVVSYGPTPCGLK 378
            :|.::.   .|.:....:|||.......|.|||||||||                  |...||:.
  Fly   188 DCEKQL---DRKMPPNIICAGAYNNKTLCFGDSGGPLLL------------------GRQVCGIN 231

  Fly   379 GW---------PGVYTRVEAYLNWIENNV 398
            .|         |.||..|..|..:|:..:
  Fly   232 TWTFKCGNNEKPDVYMGVRYYAKFIKRTI 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MP1	NP_001303421.1	CLIP	29..91	CDD:288855
		Tryp_SPc	137..394	CDD:214473	65/280 (23%)
		Tryp_SPc	138..397	CDD:238113	65/282 (23%)
CG4815	NP_651607.1	Tryp_SPc	49..259	CDD:304450	62/268 (23%)
CG4815	NP_651607.1	Trypsin	49..256	CDD:278516	61/265 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436622
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030