DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MP1 and CG5255

DIOPT Version :9

Sequence 1:	NP_001303421.1	Gene:	MP1 / 40541	FlyBaseID:	FBgn0027930	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_650604.1	Gene:	CG5255 / 42073	FlyBaseID:	FBgn0038485	Length:	273	Species:	Drosophila melanogaster

Alignment Length:	265	Identity:	71/265 - (26%)
Similarity:	119/265 - (44%)	Gaps:	41/265 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 DRVVGGNETTKREFPWMALIEYTKPGNVKGHHCGGSLINHRYVLTAAHCVSAIPSDWELTGVRLG 200
            :|:|||.|......|:...::....|   .|.|||::|:.|:::|||||...    .:.|..|:
  Fly    28 NRIVGGEEAAAGLAPYQISLQGIGSG---AHSCGGAIIDERWIITAAHCTRG----RQATAFRV- 84

  Fly   201 EWDASTNPDCTVGKNGRRDCNEPYVDYPVEERI-PHPQYPGNSRDQLNDIALLRLRDEVQYSDFI 264
                         ..|.:|.::....|...:|| .|..|.  .|...||||||.|.:.:.:.:..
  Fly    85 -------------LTGTQDLHQNGSKYYYPDRIVEHSNYA--PRKYRNDIALLHLNESIVFDNAT 134

  Fly   265 LPVCLPTLASQHNNIFLGRKVVVAGWGRTETNFTSNIKLKA-ELDTVPTSECNQRYATQRRTVTT 328
            .||.|     .|..:..|.::::.|||..........:|:: |::.||..:|...:....| |..
  Fly   135 QPVEL-----DHEALVPGSRLLLTGWGTLSLGGDVPARLQSLEVNYVPFEQCRAAHDNSTR-VDI 193

  Fly   329 KQMCAGGVEGVDSCRGDSGGPLLLEDYSNGNSNYYIAGVVSYGPTPCGLKGWPGVYTRVEAYLNW 393
            ..:|....:|..:|.|||||||:    .||.    :..:|::| .||. ||:|..:..:..|.::
  Fly   194 GHVCTFNDKGRGACHGDSGGPLV----HNGK----LVALVNWG-LPCA-KGYPDAHASISYYHDF 248

  Fly   394 IENNV 398
            |..::
  Fly   249 IRTHL 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MP1	NP_001303421.1	CLIP	29..91	CDD:288855
		Tryp_SPc	137..394	CDD:214473	70/258 (27%)
		Tryp_SPc	138..397	CDD:238113	70/260 (27%)
CG5255	NP_650604.1	Tryp_SPc	29..249	CDD:214473	70/258 (27%)
CG5255	NP_650604.1	Tryp_SPc	30..252	CDD:238113	70/260 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437258
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940