DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MP1 and CG5246

DIOPT Version :9

Sequence 1:	NP_001303421.1	Gene:	MP1 / 40541	FlyBaseID:	FBgn0027930	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_650603.1	Gene:	CG5246 / 42072	FlyBaseID:	FBgn0038484	Length:	272	Species:	Drosophila melanogaster

Alignment Length:	267	Identity:	77/267 - (28%)
Similarity:	123/267 - (46%)	Gaps:	53/267 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 RVVGGNETTKREFPWMALIEYTKPGNVKGHH-CGGSLINHRYVLTAAHCVSAIPSDWELTGVRLG 200
            ||:||.::.....|:...|.     |..|.| ||||:|..:::||||||:     :|.:..:::
  Fly    41 RVIGGVDSPTGFAPYQVSIM-----NTFGEHVCGGSIIAPQWILTAAHCM-----EWPIQYLKI- 94

  Fly   201 EWDASTNPDCTVGKNGRRDCNEPYVDYPVEERIPH-----PQYPGNSRDQLNDIALLRLRDEVQY 260
                         ..|..|...|..:|.|:....|     |.|.       |||||:.....:.|
  Fly    95 -------------VTGTVDYTRPGAEYLVDGSKIHCSHDKPAYH-------NDIALIHTAKPIVY 139

  Fly   261 SDFILPVCLPTLASQHNNIFLGRKVVVAGWGRTET--NFTSNIKLKAELDTVPTSECNQRYATQR 323
            .|...|:   .|||:.:...:|.|:.:.|||.|:|  .:::.:: |.:|:.:....|..| ....
  Fly   140 DDLTQPI---KLASKGSLPKVGDKLTLTGWGSTKTWGRYSTQLQ-KIDLNYIDHDNCQSR-VRNA 199

  Fly   324 RTVTTKQMCAGGVEGVDSCRGDSGGPLLLEDYSNGNSNYYIAGVVSYGPTPCGLKGWPGVYTRVE 388
            ..::...:|....||..||.|||||||:       ::|..:.|||::|.. |.: |:|.|:..|.
  Fly   200 NWLSEGHVCTFTQEGEGSCHGDSGGPLV-------DANQTLVGVVNWGEA-CAI-GYPDVFGSVA 255

  Fly   389 AYLNWIE 395
            .|.:|||
  Fly   256 YYHDWIE 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MP1	NP_001303421.1	CLIP	29..91	CDD:288855
		Tryp_SPc	137..394	CDD:214473	74/264 (28%)
		Tryp_SPc	138..397	CDD:238113	76/266 (29%)
CG5246	NP_650603.1	Tryp_SPc	41..261	CDD:214473	74/264 (28%)
CG5246	NP_650603.1	Tryp_SPc	42..263	CDD:238113	76/266 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437257
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940