DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MP1 and CG18223

DIOPT Version :9

Sequence 1:	NP_001303421.1	Gene:	MP1 / 40541	FlyBaseID:	FBgn0027930	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_649077.1	Gene:	CG18223 / 40068	FlyBaseID:	FBgn0036832	Length:	322	Species:	Drosophila melanogaster

Alignment Length:	309	Identity:	80/309 - (25%)
Similarity:	125/309 - (40%)	Gaps:	72/309 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 LLPMAPNCGENFGDRVVGGNETTKR-EFPW------MALIEYT------KPGNVKG--HHCGGSL 172
            |||:. :.|:..|...|  ....|| ..|:      :.|.:|.      :|..:.|  |.|||.:
  Fly    22 LLPIL-DAGDPIGSHFV--RRRAKRLSSPYFDKEKTLVLAKYVVSIRSRRPHKLFGDNHFCGGVI 83

  Fly   173 INHRYVLTAAHCV----SAIPSDWELTGVRLGEWDASTNPDCTVGKNGRRDCNEPYVDYPVEER- 232
            |:..|:||:|||.    ..:.....|..|.     .:||          |..:...:...:|.:
  Fly    84 ISRTYILTSAHCAMDKRKIVHRSRVLVVVA-----GTTN----------RLKSRKGLSLNMEVKK 133

  Fly   233 --IPHPQYPGNSRDQLNDIALLRLRDEVQYSDFILPVC-LPTLASQHNNIFLGRKVVVAGWGRTE 294
              :|......|:    |:|||:.|..::...:.::.|. |||...:.     |....|.||||..
  Fly   134 IFVPDKFTVFNT----NNIALMMLAKKLPLDNPLVGVINLPTADPEP-----GLNYTVLGWGRIF 189

  Fly   295 TN--FTSNIKLKAELDTVPTSECNQRYATQRRTVTTKQMCAGGVEGV---DSCRGDSGGPLLLED 354
            ..  ..|:| |..:::.:|...|.::.    .....:.||||.:...   :.|.||:|.||:.
  Fly   190 KGGPLASDI-LHIDVELLPRDICEKKV----HIFKEEMMCAGNLNNTMDENPCAGDTGSPLIF-- 247

  Fly   355 YSNGNSNYYIAGVVSYGPTPCGLKGWPGVYTRVEAYLNWIE---NNVRA 400
                  |..:.||||| ...||.|..|.:||.|..:::||.   ||..|
  Fly   248 ------NETVFGVVSY-RVGCGSKTLPSIYTNVYMHMDWINGIMNNNEA 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MP1	NP_001303421.1	CLIP	29..91	CDD:288855
		Tryp_SPc	137..394	CDD:214473	70/284 (25%)
		Tryp_SPc	138..397	CDD:238113	72/289 (25%)
CG18223	NP_649077.1	Tryp_SPc	60..283	CDD:238113	67/260 (26%)
CG18223	NP_649077.1	Tryp_SPc	60..280	CDD:214473	65/257 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437256
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030