DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MP1 and CG10469

DIOPT Version :9

Sequence 1:	NP_001303421.1	Gene:	MP1 / 40541	FlyBaseID:	FBgn0027930	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_648025.1	Gene:	CG10469 / 38696	FlyBaseID:	FBgn0035678	Length:	267	Species:	Drosophila melanogaster

Alignment Length:	274	Identity:	75/274 - (27%)
Similarity:	138/274 - (50%)	Gaps:	38/274 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 GENFGD-RVVGGNETTKREFPW-MALIEYTKPGNVKGHHCGGSLINHRYVLTAAHCVSAIPSD-W 192
            |:..|. |::.|.....::.|: :.|:.|.:....:.:.|||:::::|:::|||||:....|: |
  Fly    16 GQETGSLRIMNGTAAKAKQLPYQVGLLCYFEGSKDEPNMCGGTILSNRWIITAAHCLQDPKSNLW 80

  Fly   193 ELTGVRLGEWDASTNPDCTVGKNGRRDCNEPYVDYPVEERIPHPQYPGNSRDQLNDIALLRLRDE 257
            ::. :.:|:..:..:.:..|        |..|.       |.|.::  :.:...|||||::|..:
  Fly    81 KVL-IHVGKVKSFDDKEIVV--------NRSYT-------IVHKKF--DRKTVTNDIALIKLPKK 127

  Fly   258 VQYSDFILPVCLPTLASQHNNIFLGRKVVVAGWGRTETNFTSNIKLKAELDTVPTSECNQRYATQ 322
            :.::.:|.|..||:.    ...:.|||.:::|||.|.....|.:........:...||.:::..|
  Fly   128 LTFNKYIQPAKLPSA----KKTYTGRKAIISGWGLTTKQLPSQVLQYIRAPIISNKECERQWNKQ 188

  Fly   323 -----RRTVTTKQMCAGGVEGVDSCRGDSGGPLLLEDYSNGNSNYYIAGVVSYG-PTPCGLKGWP 381
                 ::.|....:|....:|: .||||||||::|:|.|.     .:.|:||:| ...|.|| .|
  Fly   189 LGGKSKKVVHNGFICIDSKKGL-PCRGDSGGPMVLDDGSR-----TLVGIVSHGFDGECKLK-LP 246

  Fly   382 GVYTRVEAYLNWIE 395
            .|.|||.:||.||:
  Fly   247 DVSTRVSSYLKWIK 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MP1	NP_001303421.1	CLIP	29..91	CDD:288855
		Tryp_SPc	137..394	CDD:214473	71/264 (27%)
		Tryp_SPc	138..397	CDD:238113	72/266 (27%)
CG10469	NP_648025.1	Tryp_SPc	23..259	CDD:214473	71/264 (27%)
CG10469	NP_648025.1	Tryp_SPc	24..260	CDD:238113	71/264 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436457
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940