DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MP1 and CG10472

DIOPT Version :9

Sequence 1:	NP_001303421.1	Gene:	MP1 / 40541	FlyBaseID:	FBgn0027930	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_648017.1	Gene:	CG10472 / 38688	FlyBaseID:	FBgn0035670	Length:	290	Species:	Drosophila melanogaster

Alignment Length:	282	Identity:	83/282 - (29%)
Similarity:	134/282 - (47%)	Gaps:	45/282 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 PMAPNCGENF-GDRVVGGNETTKREFPW-MALIEYTKPGNVKGHHCGGSLINHRYVLTAAHCVSA 187
            ||....||.. ..|:.||......:||: :.|:.|...|   ...|||::|:.|:::|||||..:
  Fly    33 PMPKVHGETLPSGRITGGQIAEPNQFPYQVGLLLYITGG---AAWCGGTIISDRWIITAAHCTDS 94

  Fly   188 IPSDWELTGVRLGEWDASTNPDCTVGKNGRRDCNEP-----YVDYPVEERIPHPQYPGNSRDQLN 247
            :     .|||           |..:|.:.|.:..|.     :|:  .:..|.|..:...:  ..|
  Fly    95 L-----TTGV-----------DVYLGAHDRTNAKEEGQQIIFVE--TKNVIVHEDWIAET--ITN 139

  Fly   248 DIALLRLRDEVQYSDFILPVCLPTLASQHNNIFLGRKVVVAGWGRTETNFTSNIKLKAELDTVP- 311
            ||:|::|...::::.:|.|..||..:..::. :.|...:.:|||:...:.|....: .:..|||
  Fly   140 DISLIKLPVPIEFNKYIQPAKLPVKSDSYST-YGGENAIASGWGKISDSATGATDI-LQYATVPI 202

  Fly   312 --TSECNQRYATQRRTVTTKQMCAGGVEGVDSCRGDSGGPLLLEDYSNGNSNYYIAGVVSYG-PT 373
              .|.|:..|.   ..|....:|.....|:.:|.|||||||:|:|.||     .:.|..|:| ..
  Fly   203 MNNSGCSPWYF---GLVAASNICIKTTGGISTCNGDSGGPLVLDDGSN-----TLIGATSFGIAL 259

  Fly   374 PCGLKGWPGVYTRVEAYLNWIE 395
            .|.: |||||:||:..||:|||
  Fly   260 GCEV-GWPGVFTRITYYLDWIE 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MP1	NP_001303421.1	CLIP	29..91	CDD:288855
		Tryp_SPc	137..394	CDD:214473	76/266 (29%)
		Tryp_SPc	138..397	CDD:238113	78/268 (29%)
CG10472	NP_648017.1	Tryp_SPc	46..279	CDD:214473	76/266 (29%)
CG10472	NP_648017.1	Tryp_SPc	47..282	CDD:238113	78/268 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436292
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940