DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MP1 and Prss48

DIOPT Version :9

Sequence 1:	NP_001303421.1	Gene:	MP1 / 40541	FlyBaseID:	FBgn0027930	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_001001650.1	Gene:	Prss48 / 368202	MGIID:	2685865	Length:	312	Species:	Mus musculus

Alignment Length:	290	Identity:	98/290 - (33%)
Similarity:	131/290 - (45%)	Gaps:	52/290 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 SGTKLLPMAPNCGE--NFGDRVVGGNETTKREFPWMALI--EYTKPGNVKGHHCGGSLINHRYVL 179
            |.||...:...||.  :.| |:|||.:.....:||...:  :||       |.||||||:..:||
Mouse    20 SFTKKKNLQSVCGRPVHTG-RIVGGQDAALGRWPWQVSLRFDYT-------HSCGGSLISDHWVL 76

  Fly   180 TAAHCVSAIPSDWE--LTGVRLGEWDASTNPDCTVGKNGRRDCNEPYVDYPVEERIPHPQYPGNS 242
            |||||   |...|.  |..|.||..|...:   :.||       |.||     .||   ..|...
Mouse    77 TAAHC---IKKTWYSFLYSVWLGSIDREYS---STGK-------EYYV-----SRI---AIPDKH 120

  Fly   243 RDQLNDIALLRLRDEVQYSDFILPVCLPTLASQHNNIFLGRKVVVAGWGRTETNFTSNIKLKAEL 307
            |....|||||:|...|.:|..|||:|||.::.|   :.:.....|.|||:.:.....:...:.|:
Mouse   121 RHTEADIALLKLSSRVTFSSVILPICLPNISKQ---LTVPASCWVTGWGQNQEGHYPSTLQELEV 182

  Fly   308 DTVPTSECNQRY-------ATQRRTVTTKQMCAGGVEG-VDSCRGDSGGPLLLEDYSNGNSNYYI 364
            ..:.:..|.|.|       ....|.:.....|||..:. .|||:|||||||    ..:.:..:.:
Mouse   183 PVISSEACEQLYNPIGVFLPDLERVIKEDMFCAGERQSRKDSCKGDSGGPL----SCHIDGVWRL 243

  Fly   365 AGVVSYGPTPCGLKGWPGVYTRVEAYLNWI 394
            .||||:| ..|| |..|||||.|..|..||
Mouse   244 MGVVSWG-LECG-KDLPGVYTNVTYYQKWI 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MP1	NP_001303421.1	CLIP	29..91	CDD:288855
		Tryp_SPc	137..394	CDD:214473	90/268 (34%)
		Tryp_SPc	138..397	CDD:238113	91/269 (34%)
Prss48	NP_001001650.1	Tryp_SPc	39..271	CDD:214473	90/268 (34%)
Prss48	NP_001001650.1	Tryp_SPc	40..274	CDD:238113	91/269 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910