DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MP1 and prss60.3

DIOPT Version :9

Sequence 1:	NP_001303421.1	Gene:	MP1 / 40541	FlyBaseID:	FBgn0027930	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	278	Identity:	89/278 - (32%)
Similarity:	132/278 - (47%)	Gaps:	43/278 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 CGE-NFGDRVVGGNETTKREFPWMALIEYTKPGNVKGHHCGGSLINHRYVLTAAHCVSAIPSDWE 193
            ||: ....|:|||...:...:||...:...|.|   ||.||||||:..:|||||||:|.:
Zfish    27 CGQAPLNTRIVGGVNASPGSWPWQVSLHSPKYG---GHFCGGSLISSEWVLTAAHCLSGV----- 83

  Fly   194 LTGVRLGEWDASTNPDCTVGKNGRRDCNEPYVDYPVEERIPHPQYPGNSRDQLNDIALLRLRDEV 258
                      :.|.....:|:..::..|.......|.:...|..|..|:.|  ||||||||...|
Zfish    84 ----------SETTLVVYLGRRTQQGINIYETSRNVAKSFVHSSYNSNTND--NDIALLRLSSAV 136

  Fly   259 QYSDFILPVCLPTLASQHNNIFLGRKVVVAGWGRTETNFTSNIKLKAE-------LDTVPTSECN 316
            .::::|.|||   ||:|::....|....:.|||    :..:.:.|.|.       :..|....||
Zfish   137 TFTNYIRPVC---LAAQNSVYSAGTSSWITGWG----DIQAGVNLPAPGILQETMIPVVANDRCN 194

  Fly   317 QRYATQRRTVTTKQMCAGGVE-GVDSCRGDSGGPLLLEDYSNGNSNYYIAGVVSYGPTPCGLKGW 380
            ....:  .|||...:|||..: |.|:|:||||||::    :...:.:..||:.|:| ..|.....
Zfish   195 ALLGS--GTVTNNMICAGLTQGGKDTCQGDSGGPMV----TRLCTVWVQAGITSWG-YGCADPNS 252

  Fly   381 PGVYTRVEAYLNWIENNV 398
            |||||||..|.:||.:.:
Zfish   253 PGVYTRVSQYQSWISSKI 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MP1	NP_001303421.1	CLIP	29..91	CDD:288855
		Tryp_SPc	137..394	CDD:214473	85/264 (32%)
		Tryp_SPc	138..397	CDD:238113	86/266 (32%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	86/266 (32%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900