DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MP1 and Prss22

DIOPT Version :9

Sequence 1:	NP_001303421.1	Gene:	MP1 / 40541	FlyBaseID:	FBgn0027930	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_001100454.1	Gene:	Prss22 / 302971	RGDID:	1310880	Length:	307	Species:	Rattus norvegicus

Alignment Length:	293	Identity:	93/293 - (31%)
Similarity:	148/293 - (50%)	Gaps:	60/293 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 APNCGE-NFGDRVVGGNETTKREFPWMALIEYTKPGNVKGHHCGGSLINHRYVLTAAHCVSA--- 187
            :|:||: ...:|||||.::...::||  ::...|.|:   |||.|||:.:|:|::||||.|:
  Rat    38 SPDCGKPQQLNRVVGGEDSADAQWPW--IVSILKNGS---HHCAGSLLTNRWVVSAAHCFSSNMD 97

  Fly   188 IPSDWELTGVRLGEWDASTNPDCTVGKNGRRDCNEPYVDYPVEERIPHPQYPGNSRDQLN--DIA 250
            .||.:   .|.||.|... ||.....|.|            :...:|||:|   ||.:..  |||
  Rat    98 KPSPY---SVLLGAWKLG-NPGPRSQKVG------------IASVLPHPRY---SRKEGTHADIA 143

  Fly   251 LLRLRDEVQYSDFILPVCLPTLASQH----NNIFLGRKVVVAGWGRTETNFTSNIKL-------K 304
            |:||...:|:|:.|||:|||. :|.|    .|.:      :||||    :....:.|       |
  Rat   144 LVRLERPIQFSERILPICLPD-SSVHLPPNTNCW------IAGWG----SIQDGVPLPRPQTLQK 197

  Fly   305 AELDTVPTSECNQRY--ATQRRTVTTKQMCAGGVEGV-DSCRGDSGGPLLLEDYSNGNSNYYIAG 366
            .::..:....|...|  ...:..:|...:|||.:||. |:|.|||||||:.:    .:.::.:.|
  Rat   198 LKVPIIDPELCKSLYWRGAGQEAITEDMLCAGYLEGKRDACLGDSGGPLMCQ----VDDHWLLTG 258

  Fly   367 VVSYGPTPCGLKGWPGVYTRVEAYLNWIENNVR 399
            ::|:| ..|..:..|||||.:.|:..|::..|:
  Rat   259 IISWG-EGCAERNRPGVYTSLLAHRPWVQRIVQ 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MP1	NP_001303421.1	CLIP	29..91	CDD:288855
		Tryp_SPc	137..394	CDD:214473	88/275 (32%)
		Tryp_SPc	138..397	CDD:238113	88/277 (32%)
Prss22	NP_001100454.1	Tryp_SPc	49..285	CDD:214473	88/275 (32%)
Prss22	NP_001100454.1	Tryp_SPc	50..288	CDD:238113	88/277 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910