DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MP1 and Prss30

DIOPT Version :9

Sequence 1:	NP_001303421.1	Gene:	MP1 / 40541	FlyBaseID:	FBgn0027930	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_955403.2	Gene:	Prss30 / 287106	RGDID:	735142	Length:	304	Species:	Rattus norvegicus

Alignment Length:	270	Identity:	87/270 - (32%)
Similarity:	128/270 - (47%)	Gaps:	37/270 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 RVVGGNETTKREFPWMALIEYTKPGNVKGHHCGGSLINHRYVLTAAHCVSAIPSDWELTGVRLGE 201
            ::|||.:..:..:||...:...|    :||.||||||:..:|||||||... |.:.....|::|.
  Rat    30 KIVGGQDAPEGRWPWQVSLRTEK----EGHICGGSLIHEVWVLTAAHCFCR-PLNSSFYHVKVGG 89

  Fly   202 WDAS-TNPDCTVGKNGRRDCNEPYVDYPVEERIPHPQYPGNSRDQLNDIALLRLRDEVQYSDFIL 265
            ...| |.|..|:              ..|.....:|.|....... .|||||||...:|.|.| .
  Rat    90 LTLSLTEPHSTL--------------VAVRNIFVYPTYLWEDASS-GDIALLRLDTPLQPSQF-S 138

  Fly   266 PVCLPTLASQHNNIFLGRKVVVAGWGRTETNFTSNIKLKAELDTVPTSECNQRY------ATQRR 324
            |||||...:.   :..|....|.|||.|.....:::..:..:..:.:.:|.:.|      .:.:|
  Rat   139 PVCLPQAQAP---LTPGTVCWVTGWGATHERELASVLQELAVPLLDSEDCERMYHIGETSLSGKR 200

  Fly   325 TVTTKQMCAGGVEG-VDSCRGDSGGPLLLEDYSNGNSNYYIAGVVSYGPTPCGLKGWPGVYTRVE 388
            .:.:..:|||.||| .|||:|||||||:...    ||::...|:.|:| ..|.....|||||||.
  Rat   201 VIQSDMLCAGFVEGQKDSCQGDSGGPLVCAI----NSSWIQVGITSWG-IGCARPNKPGVYTRVP 260

  Fly   389 AYLNWIENNV 398
            .|::||:..:
  Rat   261 DYVDWIQRTL 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MP1	NP_001303421.1	CLIP	29..91	CDD:288855
		Tryp_SPc	137..394	CDD:214473	85/264 (32%)
		Tryp_SPc	138..397	CDD:238113	87/266 (33%)
Prss30	NP_955403.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810