DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MP1 and CG18420

DIOPT Version :9

Sequence 1:	NP_001303421.1	Gene:	MP1 / 40541	FlyBaseID:	FBgn0027930	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_995715.1	Gene:	CG18420 / 2768924	FlyBaseID:	FBgn0028866	Length:	299	Species:	Drosophila melanogaster

Alignment Length:	270	Identity:	80/270 - (29%)
Similarity:	122/270 - (45%)	Gaps:	41/270 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 CGE----NFGDRVVGGNETTKREFPWMALIEYTKPGNVKGHHCGGSLINHRYVLTAAHCVSAIPS 190
            ||.    ..|.|:|.|....:...||||.:..:....:    |||:||:.|.|||||||.  ||:
  Fly    31 CGTRSPLKLGPRIVNGKVAVRNSSPWMAFLHTSSNQFI----CGGTLISRRLVLTAAHCF--IPN 89

  Fly   191 DWELTGVRLGEWDASTNPDCTVGKNGRRDCNEPYVDYPVEERIPHPQYPGNSRDQLNDIALLRLR 255
            ...:  |||||::...        .|.|:      ::.|.....|..|..|:  ..||||||||.
  Fly    90 TTIV--VRLGEYNRKL--------KGYRE------EHQVNRTFQHRFYDPNT--HANDIALLRLV 136

  Fly   256 DEVQYSDFILPVCLPTLASQHNNIFLGRKVVVAGWGRTETNFTSNIKLKAELDTVPTSECNQRYA 320
            ..|.|...|.|:|:...||..::|...:.:...||||||:...|:.....::...|:..|
  Fly   137 SNVVYKANIRPICIMWDASWKHHIDSIKVLTGTGWGRTESMHDSSELRTLDISRQPSKMC----- 196

  Fly   321 TQRRTVTTKQMCAGGVEGVDSCRGDSGGPL-LLEDYSNGNSNYYIAGVVSYGPTPCGLKGWPGVY 384
             ...:|.:.|.|||.... :.|.||:|||: .:..|.  |:..::...::.....|..   |.|:
  Fly   197 -AFGSVLSNQFCAGNWNS-NLCIGDTGGPVGAMVRYR--NAFRFVQVGIAITNKRCQR---PSVF 254

  Fly   385 TRVEAYLNWI 394
            |.|.:::.:|
  Fly   255 TDVMSHIEFI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MP1	NP_001303421.1	CLIP	29..91	CDD:288855
		Tryp_SPc	137..394	CDD:214473	76/257 (30%)
		Tryp_SPc	138..397	CDD:238113	76/258 (29%)
CG18420	NP_995715.1	Tryp_SPc	42..264	CDD:214473	76/257 (30%)
CG18420	NP_995715.1	Tryp_SPc	43..267	CDD:238113	76/258 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463625
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940